The transition from genomics to phenomics in personalized population health
Modern health care faces several serious challenges, including an ageing population and
its inherent burden of chronic diseases, rising costs and marginal quality metrics. By …
its inherent burden of chronic diseases, rising costs and marginal quality metrics. By …
Dynamic lipidome alterations associated with human health, disease and ageing
Lipids can be of endogenous or exogenous origin and affect diverse biological functions,
including cell membrane maintenance, energy management and cellular signalling. Here …
including cell membrane maintenance, energy management and cellular signalling. Here …
Learning across diverse biomedical data modalities and cohorts: Challenges and opportunities for innovation
In healthcare, machine learning (ML) shows significant potential to augment patient care,
improve population health, and streamline healthcare workflows. Realizing its full potential …
improve population health, and streamline healthcare workflows. Realizing its full potential …
Multi-omics approaches in psychoneuroimmunology and health research: conceptual considerations and methodological recommendations
The field of psychoneuroimmunology (PNI) has grown substantially in both relevance and
prominence over the past 40 years. Notwithstanding its impressive trajectory, a majority of …
prominence over the past 40 years. Notwithstanding its impressive trajectory, a majority of …
Towards nutrition with precision: unlocking biomarkers as dietary assessment tools
C Cuparencu, T Bulmuş-Tüccar, J Stanstrup… - Nature …, 2024 - nature.com
Precision nutrition requires precise tools to monitor dietary habits. Yet current dietary
assessment instruments are subjective, limiting our understanding of the causal …
assessment instruments are subjective, limiting our understanding of the causal …
Blood-based multiomics-guided detection of a precancerous pancreatic tumor
MA Anwar, AH Keshteli, H Yang, W Wang… - OMICS: A Journal of …, 2024 - liebertpub.com
Over a decade ago, longitudinal multiomics analysis was pioneered for early disease
detection and individually tailored precision health interventions. However, high sample …
detection and individually tailored precision health interventions. However, high sample …
Revolutionizing blood Collection: innovations, applications, and the potential of Microsampling Technologies for monitoring metabolites and lipids
Blood serves as the primary global biological matrix for health surveillance, disease
diagnosis, and response to drug treatment, holding significant promise for personalized …
diagnosis, and response to drug treatment, holding significant promise for personalized …
A Narrative Review of Cytokine Networks: Pathophysiological and Therapeutic Implications for Inflammatory Bowel Disease Pathogenesis
M Vebr, R Pomahačová, J Sýkora, J Schwarz - Biomedicines, 2023 - mdpi.com
Inflammatory bowel disease (IBD) is a lifelong inflammatory immune mediated disorder,
encompassing Crohn's disease (CD) and ulcerative colitis (UC); however, the cause and …
encompassing Crohn's disease (CD) and ulcerative colitis (UC); however, the cause and …
Patchwork learning: A paradigm towards integrative analysis across diverse biomedical data sources
Machine learning (ML) in healthcare presents numerous opportunities for enhancing patient
care, population health, and healthcare providers' workflows. However, the real-world …
care, population health, and healthcare providers' workflows. However, the real-world …
Characterizing human postprandial metabolic response using multiway data analysis
Introduction Analysis of time-resolved postprandial metabolomics data can improve our
understanding of the human metabolism by revealing similarities and differences in …
understanding of the human metabolism by revealing similarities and differences in …