Nutritional immunity: the battle for nutrient metals at the host–pathogen interface

CC Murdoch, EP Skaar - Nature Reviews Microbiology, 2022 - nature.com
Trace metals are essential micronutrients required for survival across all kingdoms of life.
From bacteria to animals, metals have critical roles as both structural and catalytic cofactors …

Recent Advances in the Pursuit of an Effective Acinetobacter baumannii Vaccine

PS Gellings, AA Wilkins, LA Morici - Pathogens, 2020 - mdpi.com
Acinetobacter baumannii has been a major cause of nosocomial infections for decades. The
absence of an available vaccine coupled with emerging multidrug resistance has prevented …

Zinc: Multidimensional effects on living organisms

MP Cuajungco, MS Ramirez, ME Tolmasky - Biomedicines, 2021 - mdpi.com
Zinc is a redox-inert trace element that is second only to iron in abundance in biological
systems. In cells, zinc is typically buffered and bound to metalloproteins, but it may also exist …

Acinetobacter baumannii subunit vaccines: recent progress and challenges

YT Lau, HS Tan - Critical reviews in microbiology, 2024 - Taylor & Francis
Acinetobacter baumannii is a Gram-negative, opportunistic pathogen that causes
nosocomial infection with a high mortality rate in immunocompromised individuals. With the …

Non-antibiotic prevention and treatment against Acinetobacter baumannii infection: Are vaccines and adjuvants effective strategies?

Y Hu, X Zhang, S Deng, C Yue, X Jia… - Frontiers in Microbiology, 2023 - frontiersin.org
Acinetobacter baumannii (A. baumannii) is a Gram-negative opportunistic pathogen widely
attached to the surface of medical instruments, making it one of the most common pathogens …

Vaccines for multidrug resistant Gram negative bacteria: Lessons from the past for guiding future success

M Lopez-Siles, A Corral-Lugo… - FEMS microbiology …, 2021 - academic.oup.com
Antimicrobial resistance is a major threat to global public health. Vaccination is an effective
approach for preventing bacterial infections, however it has not been successfully applied to …

Actinobacillus pleuropneumoniae, surface proteins and virulence: a review

MM Soto Perezchica, AL Guerrero Barrera… - Frontiers in Veterinary …, 2023 - frontiersin.org
Actinobacillus pleuropneumoniae (App) is a globally distributed Gram-negative bacterium
that produces porcine pleuropneumonia. This highly contagious disease produces high …

Hybrid antigens expressing surface loops of BauA from Acinetobacter baumannii are capable of inducing protection against infection

S Chaudhuri, I Rasooli, RH Oskouei… - Frontiers in …, 2022 - frontiersin.org
Acinetobacter baumannii is a human bacterial pathogen of increasing concern in clinical
settings due to the emergence of antibiotic resistant strains and the lack of effective …

Facing the challenges of multidrug-resistant Acinetobacter baumannii: progress and prospects in the vaccine development

NA Mat Rahim, HY Lee, U Strych… - Human Vaccines & …, 2021 - Taylor & Francis
ABSTRACT In 2017, the World Health Organization (WHO) named A. baumannii as one of
the three antibiotic-resistant bacterial species on its list of global priority pathogens in dire …

Combination of BauA and OmpA elicit immunoprotection against Acinetobacter baumannii in a murine sepsis model

M Tamehri, I Rasooli, M Pishgahi, A Jahangiri… - Microbial …, 2022 - Elsevier
Aims Acinetobacter baumannii causes severe nosocomial infections and is a difficult-to-treat
pathogen due to the development of multidrug-resistant (MDR) strains. Vaccines and …