Circulating tumor DNA as biomarkers for cancer detection

X Han, J Wang, Y Sun - Genomics, Proteomics and …, 2017 - academic.oup.com
Detection of circulating tumor DNAs (ctDNAs) in cancer patients is an important component
of cancer precision medicine ctDNAs. Compared to the traditional physical and biochemical …

The clinical utilization of circulating cell free DNA (CCFDNA) in blood of cancer patients

YI Elshimali, H Khaddour, M Sarkissyan, Y Wu… - International journal of …, 2013 - mdpi.com
Qualitative and quantitative testing of circulating cell free DNA (CCFDNA) can be applied for
the management of malignant and benign neoplasms. Detecting circulating DNA in cancer …

Methylated circulating tumor DNA in blood: power in cancer prognosis and response

K Warton, KL Mahon, G Samimi - Endocrine-related cancer, 2016 - erc.bioscientifica.com
The aim of the present study was to perform a systematic review of published studies to
provide a robust estimation of the use of procalcitonin (ProCT) as a diagnostic marker of …

Clinical associations of ESR2 (estrogen receptor beta) expression across thousands of primary breast tumors

H Dalal, M Dahlgren, S Gladchuk, C Brueffer… - Scientific reports, 2022 - nature.com
Estrogen receptor alpha (ERα, encoded by ESR1) is a well-characterized transcription factor
expressed in more than 75% of breast tumors and is the key biomarker to direct endocrine …

[HTML][HTML] Do circulating tumor cells, exosomes, and circulating tumor nucleic acids have clinical utility?: a report of the association for molecular pathology

B Gold, M Cankovic, LV Furtado, F Meier… - The Journal of Molecular …, 2015 - Elsevier
Diagnosing and screening for tumors through noninvasive means represent an important
paradigm shift in precision medicine. In contrast to tissue biopsy, detection of circulating …

Circulating nucleic acids as biomarkers in breast cancer

H Schwarzenbach - Breast cancer research, 2013 - Springer
During tumor development, tumor cells release their nucleic acids into the blood circulation.
This process occurs by apoptotic and necrotic cell deaths along with active cell secretion …

The role of estrogen receptor beta in breast cancer

Y Zhou, X Liu - Biomarker research, 2020 - Springer
Breast cancer, a malignant tumor originating from mammary epithelial tissue, is the most
common cancer among women worldwide. Challenges facing the diagnosis and treatment …

[HTML][HTML] Steroid hormone receptors as prognostic markers in breast cancer

MC Louie, MB Sevigny - American journal of cancer research, 2017 - ncbi.nlm.nih.gov
Despite the existence of many promising anti-cancer therapies, not all breast cancers are
equally treatable, due partly to the fact that focus has been primarily on a few select breast …

[HTML][HTML] Preliminary analysis of the association between methylation of the ACE2 promoter and essential hypertension

R Fan, SQ Mao, TL Gu, FD Zhong… - Molecular …, 2017 - spandidos-publications.com
The aim of the present study was to investigate whether methylation of the angiotensin I
converting enzyme 2 (ACE2) promoter increases the risk of essential hypertension (EH). A …

Liquid biopsy prediction of axillary lymph node metastasis, cancer recurrence, and patient survival in breast cancer: A meta-analysis

JH Lee, H Jeong, JW Choi, HE Oh, YS Kim - Medicine, 2018 - journals.lww.com
Background: Liquid biopsies using circulating tumor DNA (ctDNA) and cell-free DNA
(cfDNA) have been developed for early cancer detection and patient monitoring. To …