Toll-like receptors and metabolic (dysfunction)-associated fatty liver disease

S Khanmohammadi, MS Kuchay - Pharmacological research, 2022 - Elsevier
Metabolic (dysfunction)-associated fatty liver disease (MAFLD) is characterized by the
accumulation of lipids in the liver (steatosis). In predisposed individuals, liver steatosis can …

Enterically derived high-density lipoprotein restrains liver injury through the portal vein

YH Han, EJ Onufer, LH Huang, RW Sprung… - Science, 2021 - science.org
INTRODUCTION High-density lipoprotein (HDL) participates in cholesterol homeostasis and
may also have anti-inflammatory or anti-microbial roles through its interaction with numerous …

Systematic review with meta-analysis: epidemiology of nonalcoholic fatty liver disease in patients with inflammatory bowel disease

ZY Zou, B Shen, JG Fan - Inflammatory Bowel Diseases, 2019 - academic.oup.com
Background Nonalcoholic fatty liver disease (NAFLD) is increasingly identified in patients
with inflammatory bowel disease (IBD), but there are few systematic reviews and meta …

[HTML][HTML] Conjugated linoleic acid ameliorates hepatic steatosis by modulating intestinal permeability and gut microbiota in ob/ob mice

S Gao, Y He, L Zhang, L Liu, C Qu… - Food & Nutrition …, 2022 - ncbi.nlm.nih.gov
Background Conjugated linoleic acid (CLA) is an effective supplement for reducing fat mass,
but its effect on hepatic steatosis remains controversial. Objective This study aims to …

[HTML][HTML] Metabolic dysfunction-associated steatotic liver disease: The associations between inflammatory markers, TLR4, and Cytokines IL-17A/F, and Their …

SC Coste, OH Orășan, A Cozma, V Negrean… - Biomedicines, 2024 - mdpi.com
Background: The pathogenesis of MASLD (metabolic dysfunction-associated steatotic liver
disease) is driven by environmental, genetic, metabolic, immune, and inflammatory factors …

[HTML][HTML] A Medium-Chain Fatty Acid Analogue Prevents Intestinal Failure–Associated Liver Disease in Preterm Yorkshire Piglets

SC Fligor, ST Tsikis, TI Hirsch, A Pan, K Moskowitzova… - Gastroenterology, 2023 - Elsevier
Background & Aims At least 20%–30% of patients with intestinal failure receiving long-term
parenteral nutrition will develop intestinal failure–associated liver disease (IFALD), for which …

[HTML][HTML] Influence of nonalcoholic fatty liver disease on inflammatory bowel disease hospitalizations in the United States

A Soni, A Yekula, DS Dahiya… - Annals of …, 2023 - ncbi.nlm.nih.gov
Background The reported prevalence of nonalcoholic fatty liver disease (NAFLD) in patients
with inflammatory bowel disease (IBD) is 32%. We assessed the influence of NAFLD on IBD …

Roles for bile acid signaling and nonsense-mediated ribonucleic acid decay in small bowel resection-associated liver injury

ME Tecos, AE Steinberger, J Guo, DC Rubin… - Journal of Surgical …, 2024 - Elsevier
Introduction Massive intestinal loss resulting in short bowel syndrome has been linked to
intestinal failure associated liver disease. Efforts to elucidate the driving force behind the …

Disruption of enterohepatic circulation of bile acids ameliorates small bowel resection associated hepatic injury

ME Tecos, AE Steinberger, J Guo, DC Rubin… - Journal of pediatric …, 2023 - Elsevier
Background Massive small bowel resection (SBR) is associated with liver injury and fibrosis.
Efforts to elucidate the driving force behind hepatic injury have identified multiple factors …

Hepatobiliary and pancreatic manifestations in inflammatory bowel disease: an umbrella review of meta-analyses

R Hong, Z Li, M Li, Y Dai - Therapeutic Advances in …, 2025 - journals.sagepub.com
Background: Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's
disease (CD), can affect the hepatobiliary system and pancreas, substantially impacting the …