Securines and securamines are cytotoxic alkaloids that contain reactive alkene and
heterocyclic residues embedded in skeletons comprising four to six oxidized rings. This …

A dearomative oxidation of pyrroles to Δ3‐pyrrol‐2‐ones is described, which employs a
sulfoxide as oxidant, in conjunction with a carboxylic acid anhydride and a Brønsted acid …

Bio-inspired oxidation strategies are gaining increasing interest in the synthesis of fine and
commodity chemicals. In particular, the development of catalytic oxidation systems with bio …

A domino condensation–cyclization method is developed to synthesize indolizidine
alkaloids using a P4O10/TfOH reagent system without the employment of either a catalyst or …

A simple and convenient method has been proposed for the synthesis of new isoquinoline
derivatives via intramolecular cyclization of imides obtained from acid anhydrides and 2-(3 …

Securines and securamines are alkaloids that contain a cis-enamide, neopentylic alkyl
chloride, bromoimidazole, and a pyrroloindoline that is in a reversible equilibrium with an …

Le travail de cette thèse montre l'intérêt que portent les mimes de peptides et plus
particulièrement leur utilisation dans le domaine pharmaceutique. Ce domaine trouve une …