Central nervous system targets: inhibitory interneurons in the spinal cord

DI Hughes, AJ Todd - Neurotherapeutics, 2020 - Springer
Pain is a percept of critical importance to our daily survival. In most cases, it serves both an
adaptive function by helping us respond appropriately in a potentially hostile environment …

Spinal control of locomotion: individual neurons, their circuits and functions

MP Côté, LM Murray, M Knikou - Frontiers in physiology, 2018 - frontiersin.org
Systematic research on the physiological and anatomical characteristics of spinal cord
interneurons along with their functional output has evolved for more than one century …

[图书][B] The synaptic organization of the brain

GM Shepherd - 2003 - books.google.com
It is widely recognized that the neural basis of brain function can be fully understood only by
integrating many disciplines at many levels. Studies of synaptic organization are bringing …

Down-regulation of the potassium-chloride cotransporter KCC2 contributes to spasticity after spinal cord injury

P Boulenguez, S Liabeuf, R Bos, H Bras… - Nature medicine, 2010 - nature.com
Hyperexcitability of spinal reflexes and reduced synaptic inhibition are commonly associated
with spasticity after spinal cord injury (SCI). In adults, the activation of γ-aminobutyric acidA …

Postnatal phenotype and localization of spinal cord V1 derived interneurons

FJ Alvarez, PC Jonas, T Sapir, R Hartley… - Journal of …, 2005 - Wiley Online Library
Developmental studies identified four classes (V0, V1, V2, V3) of embryonic interneurons in
the ventral spinal cord. Very little is known, however, about their adult phenotypes …

Physiological, anatomical and genetic identification of CPG neurons in the developing mammalian spinal cord

O Kiehn, SJB Butt - Progress in neurobiology, 2003 - Elsevier
The basic motor patterns underlying rhythmic limb movements during locomotion are
generated by neuronal networks located within the spinal cord. These networks are called …

Experience-dependent refinement of inhibitory inputs to auditory coincidence-detector neurons

C Kapfer, AH Seidl, H Schweizer, B Grothe - Nature neuroscience, 2002 - nature.com
The spatial arrangement of inputs on to single neurons is assumed to be crucial in accurate
signal processing. In mammals, the most precise temporal processing occurs in the context …

Mechanism of the distance‐dependent scaling of Schaffer collateral synapses in rat CA1 pyramidal neurons

MA Smith, GCR Ellis‐Davies… - The Journal of …, 2003 - Wiley Online Library
Schaffer collateral axons form excitatory synapses that are distributed across much of the
dendritic arborization of hippocampal CA1 pyramidal neurons. Remarkably, AMPA‐receptor …

Distance-dependent increase in AMPA receptor number in the dendrites of adult hippocampal CA1 pyramidal neurons

BK Andrásfalvy, JC Magee - Journal of Neuroscience, 2001 - Soc Neuroscience
The Schaffer collateral pathway provides hippocampal CA1 pyramidal cells with a fairly
homogeneous excitatory synaptic input that is spread out across several hundred …

Pax6 and engrailed 1 regulate two distinct aspects of renshaw cell development

T Sapir, EJ Geiman, Z Wang, T Velasquez… - Journal of …, 2004 - Soc Neuroscience
Many of the interneuron cell types present in the adult spinal cord contribute to the circuits
that control locomotion and posture. Little is known, however, about the embryonic origin of …