Bile acids play key roles in gut metabolism, cell signaling, and microbiome composition.
While the liver is responsible for the production of primary bile acids, microbes in the gut …

Emerging evidence strongly suggest that the human “microbiome” plays an important role in
both health and disease. Bile acids function both as detergents molecules promoting …

Bile acids (BAs) mediate the crosstalk between human and microbial cells and influence
diseases including Clostridioides difficile infection (CDI). While bile salt hydrolases (BSHs) …

Bacteria in the gastrointestinal tract produce amino acid bile acid amidates that can affect
host-mediated metabolic processes,,,,–; however, the bacterial gene (s) responsible for their …

Bile acids are synthesized from cholesterol in the liver and released into the intestine to aid
the digestion of dietary lipids. The host enzymes that contribute to bile acid synthesis in the …

Primary bile acids serve important roles in cholesterol metabolism, lipid digestion, host-
microbe interactions, and regulatory pathways in the human host. While most bile acids are …

Background Bile salt hydrolase plays an important role in bile acid-mediated signaling
pathways, which regulate lipid absorption, glucose metabolism, and energy homeostasis …

Probiotics are live microorganisms which when administered in adequate amounts confer a
health benefit on the host. Most of the probiotic bacteria currently available in the market …

Bile salt hydrolases (BSHs) catalyze the “gateway” reaction in a wider pathway of bile acid
modification by the gut microbiota. Because bile acids function as signaling molecules …

Bile acids (BA), the major components of bile, are biological detergents that facilitate the
emulsification and solubilization of dietary lipids and also display potent antimicrobial …