The relationship between COVID‐19 viral load and disease severity: a systematic review

O Dadras, AM Afsahi, Z Pashaei… - Immunity …, 2022 - Wiley Online Library
Introduction Patients with COVID‐19 may present different viral loads levels. However, the
relationship between viral load and disease severity in COVID‐19 is still unknown …

Viral load in COVID-19 patients: implications for prognosis and vaccine efficacy in the context of emerging SARS-CoV-2 variants

SJR Silva, SC Lima, RC Silva, A Kohl, L Pena - Frontiers in Medicine, 2022 - frontiersin.org
The worldwide spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) has caused an unprecedented public health crisis in the 21st century. As the pandemic …

Viral kinetics of SARS-CoV-2 following onset of COVID-19 in symptomatic patients infected with the ancestral strain and omicron BA. 2 in Hong Kong: a retrospective …

Y Lin, P Wu, TK Tsang, JY Wong, EHY Lau… - The Lancet …, 2023 - thelancet.com
Background Assessment of viral kinetics of SARS-CoV-2 can inform on host immune
responses to the virus and on the viral transmission potential. We aimed to characterise viral …

A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants

Y Han, L Tan, T Zhou, L Yang, L Carrau, LA Lacko… - Cell Stem Cell, 2022 - cell.com
Population-based studies to identify disease-associated risk alleles typically require
samples from a large number of individuals. Here, we report a human-induced pluripotent …

Severity of coronavirus disease 19: Profile of inflammatory markers and ACE (rs4646994) and ACE2 (rs2285666) gene polymorphisms in Iraqi patients

ZS Mahmood, HY Fadhil, TAA Hussein, AH Ad'hiah - Meta gene, 2022 - Elsevier
Susceptibility to coronavirus disease 2019 (COVID-19) and disease severity has recently
been associated with inflammatory markers and genetic polymorphisms of ACE (angiotensin …

A comprehensive review of BBV152 vaccine development, effectiveness, safety, challenges, and prospects

F Dotiwala, AK Upadhyay - Frontiers in Immunology, 2022 - frontiersin.org
The world has responded to the COVID-19 pandemic with unprecedented speed and vigor
in the mass vaccination campaigns, targeted to reduce COVID-19 severity and mortality …

Time-dependent increase in susceptibility and severity of secondary bacterial infections during SARS-CoV-2

AP Smith, EP Williams, TR Plunkett, M Selvaraj… - Frontiers in …, 2022 - frontiersin.org
Secondary bacterial infections can exacerbate SARS-CoV-2 infection, but their prevalence
and impact remain poorly understood. Here, we established that a mild to moderate infection …

Association of SARS-CoV-2 nucleocapsid protein mutations with patient demographic and clinical characteristics during the Delta and omicron waves

FA Alsuwairi, AN Alsaleh, MS Alsanea, AA Al-Qahtani… - Microorganisms, 2023 - mdpi.com
SARS-CoV-2 genomic mutations outside the spike protein that may increase transmissibility
and disease severity have not been well characterized. This study identified mutations in the …

Traditional Vietnamese medicine Kovir capsule in patients with mild COVID‐19: A double‐blind randomized controlled trial

HN Loc, TTN Lan, DTL Huong, NT Tuyen… - Phytotherapy …, 2022 - Wiley Online Library
Kovir capsule, a polyherbal medicine developed from Ren Shen Bai Du San formulation,
has been used in various diseases including respiratory infections. A randomized, placebo …

The kinetics of SARS-CoV-2 viremia in COVID-19 patients receiving remdesivir

A Krifors, L Karlsson, M Ekman, C Lorant… - European Journal of …, 2023 - Springer
Abstract Detection of SARS-CoV-2 RNA in serum, viremia, has been linked to disease
severity and outcome. The kinetics of viremia in patients receiving remdesivir has not been …