Lentiviral vectors (LVs) have provided an efficient way to integrate our gene of interest into
eukaryote cells. Human immunodeficiency virus (HIV)-derived LVs have been vastly studied …

Genomics and other large-scale analyses have drawn increasing attention to the potential
impacts of transposable elements (TEs) on their host genomes. However, it remains …

Cells are regularly exposed to a range of naturally occurring stress that can restrict growth or
cause lethality. In response, cells activate expression networks with hundreds of genes that …

Retroviruses and long terminal repeat retrotransposons rely on integrase (IN) to insert their
complementary DNA (cDNA) into the genome of host cells. Nevertheless, in the absence of …

Transposable elements, often referred to as “jumping genes,” have long been recognized as
genomic parasites due to their ability to integrate and disrupt normal gene function and …

Transposable elements, or 'transposons', group a wide diversity of mobile genetic elements
that can move from one location to another within the genome of their host 1. Specialized …

The urea cycle facilitates the disposal of nitrogen waste and the elimination of harmful
ammonia. Argininosuccinic aciduria (ASA), a urea cycle defect caused by a deficiency in …

We present an efficient and organized method of lithium acetate and polyethylene glycol-
based transformation of plasmid DNA into the commercially available collection of …

Nuclear pore complexes (NPCs) orchestrate cargo between the cytoplasm and nucleus and
regulate chromatin organization. NPC proteins, or nucleoporins (Nups), are required for …