Looping the genome with SMC complexes
SMC (structural maintenance of chromosomes) protein complexes are an evolutionarily
conserved family of motor proteins that hold sister chromatids together and fold genomes …
conserved family of motor proteins that hold sister chromatids together and fold genomes …
SMC complexes: from DNA to chromosomes
F Uhlmann - Nature reviews Molecular cell biology, 2016 - nature.com
SMC (structural maintenance of chromosomes) complexes—which include condensin,
cohesin and the SMC5–SMC6 complex—are major components of chromosomes in all …
cohesin and the SMC5–SMC6 complex—are major components of chromosomes in all …
Cohesin and its regulation: on the logic of X-shaped chromosomes
JHI Haarhuis, AMO Elbatsh, BD Rowland - Developmental cell, 2014 - cell.com
The X shape of chromosomes is one of the iconic images in biology. Cohesin actually
connects the sister chromatids along their entire length, from S phase until mitosis. Then …
connects the sister chromatids along their entire length, from S phase until mitosis. Then …
A replication fork determinant for the establishment of sister chromatid cohesion
Concomitant with DNA replication, the chromosomal cohesin complex establishes cohesion
between newly replicated sister chromatids. Cohesion establishment requires acetylation of …
between newly replicated sister chromatids. Cohesion establishment requires acetylation of …
Cohesin acetylation and Wapl‐Pds5 oppositely regulate translocation of cohesin along DNA
M Kanke, E Tahara, PJ Huis in't Veld… - The EMBO journal, 2016 - embopress.org
Cohesin is a ring‐shaped protein complex that plays a crucial role in sister chromatid
cohesion and gene expression. The dynamic association of cohesin with chromatin is …
cohesion and gene expression. The dynamic association of cohesin with chromatin is …
Esco1 and Esco2 regulate distinct cohesin functions during cell cycle progression
RM Alomer, EML da Silva, J Chen… - Proceedings of the …, 2017 - National Acad Sciences
Sister chromatids are tethered together by the cohesin complex from the time they are made
until their separation at anaphase. The ability of cohesin to tether sister chromatids together …
until their separation at anaphase. The ability of cohesin to tether sister chromatids together …
Establishing and dissolving cohesion during the vertebrate cell cycle
C Morales, A Losada - Current opinion in cell biology, 2018 - Elsevier
Replicated chromatids are held together from the time they emerge from the replication fork
until their separation in anaphase. This process, known as cohesion, promotes faithful DNA …
until their separation in anaphase. This process, known as cohesion, promotes faithful DNA …
Cohesion and cohesin-dependent chromatin organization
T Nishiyama - Current opinion in cell biology, 2019 - Elsevier
Cohesin, one of structural maintenance of chromosomes (SMC) complexes, forms a ring-
shaped protein complex, and mediates sister chromatid cohesion for accurate chromosome …
shaped protein complex, and mediates sister chromatid cohesion for accurate chromosome …
What AlphaFold tells us about cohesin's retention on and release from chromosomes
Cohesin is a trimeric complex containing a pair of SMC proteins (Smc1 and Smc3) whose
ATPase domains at the end of long coiled coils (CC) are interconnected by Scc1. During …
ATPase domains at the end of long coiled coils (CC) are interconnected by Scc1. During …
Cohesin, a chromatin engagement ring
S Remeseiro, A Losada - Current opinion in cell biology, 2013 - Elsevier
Cohesin is a four subunit complex, conserved from yeast to man, with the ability to hold
together two DNA segments within its ring-shaped structure. When the two segments belong …
together two DNA segments within its ring-shaped structure. When the two segments belong …