[HTML][HTML] Understanding the role of the gut microbiome and microbial metabolites in non-alcoholic fatty liver disease: current evidence and perspectives

N Vallianou, GS Christodoulatos, I Karampela… - Biomolecules, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease
worldwide. NAFLD begins as a relatively benign hepatic steatosis which can evolve to non …

[HTML][HTML] Gut microbiota bridges dietary nutrients and host immunity

L Fan, Y Xia, Y Wang, D Han, Y Liu, J Li, J Fu… - Science China Life …, 2023 - Springer
Dietary nutrients and the gut microbiota are increasingly recognized to cross-regulate and
entrain each other, and thus affect host health and immune-mediated diseases. Here, we …

[HTML][HTML] Cognitive dysfunction in non-alcoholic fatty liver disease—current knowledge, mechanisms and perspectives

K Kjærgaard, ACD Mikkelsen, CW Wernberg… - Journal of Clinical …, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) has emerged as the hepatic component of the
metabolic syndrome and now seemingly affects one-fourth of the world population. Features …

[HTML][HTML] The role of intestinal bacteria and gut–brain axis in hepatic encephalopathy

Z Chen, J Ruan, D Li, M Wang, Z Han… - Frontiers in Cellular …, 2021 - frontiersin.org
Hepatic encephalopathy (HE) is a neurological disorder that occurs in patients with liver
insufficiency. However, its pathogenesis has not been fully elucidated. Pharmacotherapy is …

[HTML][HTML] Role of gut microbiota in the pathogenesis and therapeutics of minimal hepatic encephalopathy via the gut-liver-brain axis

M Luo, RJ Xin, FR Hu, L Yao, SJ Hu… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Minimal hepatic encephalopathy (MHE) is a frequent neurological and psychiatric
complication of liver cirrhosis. The precise pathogenesis of MHE is complicated and has yet …

[HTML][HTML] A mouse model of hepatic encephalopathy: bile duct ligation induces brain ammonia overload, glial cell activation and neuroinflammation

W Claeys, L Van Hoecke, A Geerts… - Scientific Reports, 2022 - nature.com
Hepatic encephalopathy (HE) is a common complication of chronic liver disease,
characterized by an altered mental state and hyperammonemia. Insight into the brain …

[HTML][HTML] Cellular pathogenesis of hepatic encephalopathy: An update

K Lu - Biomolecules, 2023 - mdpi.com
Hepatic encephalopathy (HE) is a neuropsychiatric syndrome derived from metabolic
disorders due to various liver failures. Clinically, HE is characterized by hyperammonemia …

[HTML][HTML] The neurogliovascular unit in hepatic encephalopathy

W Claeys, L Van Hoecke, S Lefere, A Geerts… - JHEP reports, 2021 - Elsevier
Hepatic encephalopathy (HE) is a neurological complication of hepatic dysfunction and
portosystemic shunting. It is highly prevalent in patients with cirrhosis and is associated with …

[HTML][HTML] Exploring the Potential of Lactobacillus helveticus R0052 and Bifidobacterium longum R0175 as Promising Psychobiotics Using SHIME

FL De Oliveira, MK Salgaço, MT de Oliveira, V Mesa… - Nutrients, 2023 - mdpi.com
Psychobiotics are probiotics that have the characteristics of modulating central nervous
system (CNS) functions or reconciled actions by the gut–brain axis (GBA) through neural …

Hepatic encephalopathy: current and emerging treatment modalities

MA Fallahzadeh, RS Rahimi - Clinical Gastroenterology and Hepatology, 2022 - Elsevier
Hepatic encephalopathy (HE) is a potentially reversible neurocognitive complication of
cirrhosis. It has been reported in at least 30% of patients with cirrhosis and imposes a …