Advances in multiplexed techniques for the detection and quantification of microRNAs

T Jet, G Gines, Y Rondelez, V Taly - Chemical Society Reviews, 2021 - pubs.rsc.org
MicroRNA detection is currently a crucial analytical chemistry challenge: almost 2000
papers were referenced in PubMed in 2018 and 2019 for the keywords “miRNA detection …

MicroRNA: function, detection, and bioanalysis

H Dong, J Lei, L Ding, Y Wen, H Ju, X Zhang - Chemical reviews, 2013 - ACS Publications
Mature microRNAs (miRNAs) are a class of evolutionally conserved, single-stranded, small
(approximately 19− 23 nucleotides), endogenously expressed, and non-protein-coding …

A review: microRNA detection methods

T Tian, J Wang, X Zhou - Organic & biomolecular chemistry, 2015 - pubs.rsc.org
MicroRNA (miRNA) detection is of considerable significance in both disease diagnosis and
in the study of miRNA function. The importance of miRNA itself is due to the complicated …

Capillary electrophoresis

M Geiger, AL Hogerton, MT Bowser - Analytical Chemistry, 2012 - ACS Publications
Capillary electrophoresis (CE) is a field that continues to grow. All areas of CE including
theory, separation modes, instrumentation, and applications remain highly active areas of …

An electrochemical microRNAs biosensor with the signal amplification of alkaline phosphatase and electrochemical–chemical–chemical redox cycling

N Xia, Y Zhang, X Wei, Y Huang, L Liu - Analytica Chimica Acta, 2015 - Elsevier
MicroRNAs (MiRNAs) have been regarded as clinically important biomarkers and drug
discovery targets. In this work, we reported a simple and ultrasensitive electrochemical …

Recent developments and applications of capillary electrophoresis with laser-induced fluorescence detection in biological samples

E Ban, EJ Song - Journal of Chromatography B, 2013 - Elsevier
Since the human genomic project, the analysis of biomolecules using biotechnology and
biopharmaceuticals has become increasingly important for the investigation of molecular …

Noninvasive micromarkers

J Saikumar, K Ramachandran, VS Vaidya - Clinical chemistry, 2014 - academic.oup.com
BACKGROUND The recent revolutionary advances made in genome-wide sequencing
technology have transformed biology and molecular diagnostics, allowing new sRNA (small …

Universal drag tag for direct quantitative analysis of multiple microRNAs

DW Wegman, LT Cherney, GM Yousef… - Analytical …, 2013 - ACS Publications
Using microRNA (miRNA) as molecular markers of diseases requires a method for accurate
measurement of multiple miRNAs in biological samples. Direct quantitative analysis of …

Determination of RNA degradation by capillary electrophoresis with cyan light-emitted diode-induced fluorescence

TH Yang, PL Chang - Journal of Chromatography A, 2012 - Elsevier
RNA integrity plays an important role in RNA studies because poor RNA quality may have a
great impact on downstream methodologies. This study proposes a cost-effective, rapid, and …

A pico-HPLC-LIF system for the amplification-free determination of multiple miRNAs in cells

W Zhang, Z Han, Y Liang, Q Zhang, X Dou, G Guo… - Chinese Chemical …, 2021 - Elsevier
MicroRNAs are a class of important biomarkers, and the simultaneous detection of multiple
miRNAs can provide valuable information about many diseases and biological processes …