The neuromuscular junction (NMJ) is a highly specialized synapse between a motor neuron
nerve terminal and its muscle fiber that are responsible for converting electrical impulses …

Synapses, the fundamental unit in neuronal circuits, are critical for learning and memory,
perception, thinking, and reaction. The neuromuscular junction (NMJ) is a synapse formed …

Posttranslational modifications (PTMs) of tubulin, termed the “tubulin code”, play important
roles in regulating microtubule functions within subcellular compartments for specialized …

The heat shock protein 90 (Hsp90) is a molecular chaperone and a key regulator of
proteostasis under both physiological and stress conditions. In mammals, there are two …

The neuromuscular synapse is a relatively large synapse with hundreds of active zones in
presynaptic motor nerve terminals and more than ten million acetylcholine receptors …

During development, ventricular chamber maturation is a crucial step in the formation of a
functionally competent postnatal heart. Defects in this process can lead to left ventricular …

Neuromuscular junctions (NMJs) are specialized synapses in the peripheral nervous system
that allow the transmission of neuronal impulses to skeletal muscles for their contraction …

Nicotinic acetylcholine receptors (nAChRs) comprise a family of pentameric ligand-gated ion
channels widely distributed in the central and peripheric nervous system and in non …

During aging and neuromuscular diseases, there is a progressive loss of skeletal muscle
volume and function impacting mobility and quality of life. Muscle loss is often associated …

The hexanucleotide GGGGCC repeat expansion in the intronic region of C9orf72 is the most
common cause of Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) …