Increasing antimalarial drug resistance once again threatens effective antimalarial drug
treatment, malaria control, and elimination. Artemisinin combination therapies (ACTs) are …

The worldwide use of artemisinin-based combination therapies (ACTs) has contributed in
recent years to a substantial reduction in deaths resulting from Plasmodium falciparum …

Abstract Background In the six Southeast Asian countries that make up the Greater Mekong
Subregion, Plasmodium falciparum has developed resistance to derivatives of artemisinin …

Background Artemisinin resistance in Plasmodium falciparum has emerged in Southeast
Asia and now poses a threat to the control and elimination of malaria. Mapping the …

Background Recent gains in reducing the global burden of malaria are threatened by the
emergence of Plasmodium falciparum resistance to artemisinins. The discovery that …

Plasmodium falciparum resistance to artemisinin derivatives in southeast Asia threatens
malaria control and elimination activities worldwide. To monitor the spread of artemisinin …

Background A multidrug-resistant co-lineage of Plasmodium falciparum malaria, named
KEL1/PLA1, spread across Cambodia in 2008–13, causing high rates of treatment failure …

We report a large multicenter genome-wide association study of Plasmodium falciparum
resistance to artemisinin, the frontline antimalarial drug. Across 15 locations in Southeast …

Summary Background Artemisinin resistance in Plasmodium falciparum threatens to reduce
the efficacy of artemisinin combination therapies (ACTs), thus compromising global efforts to …

Background As the prevalence of artemisinin-resistant Plasmodium falciparum malaria
increases in the Greater Mekong subregion, emerging resistance to partner drugs in …