Acute flaccid myelitis: cause, diagnosis, and management

OC Murphy, K Messacar, L Benson, R Bove… - The Lancet, 2021 - thelancet.com
Acute flaccid myelitis (AFM) is a disabling, polio-like illness mainly affecting children.
Outbreaks of AFM have occurred across multiple global regions since 2012, and the disease …

Enterovirus D68 molecular and cellular biology and pathogenesis

MJ Elrick, A Pekosz, P Duggal - Journal of Biological Chemistry, 2021 - ASBMB
In recent years, enterovirus D68 (EV-D68) has advanced from a rarely detected respiratory
virus to a widespread pathogen responsible for increasing rates of severe respiratory illness …

[HTML][HTML] Enterovirus D68–associated acute flaccid myelitis, United States, 2020

S Kidd, AS Lopez, JL Konopka-Anstadt… - Emerging infectious …, 2020 - ncbi.nlm.nih.gov
Acute flaccid myelitis (AFM) is a serious neurologic condition that causes limb weakness or
paralysis in previously healthy children. Since clusters of cases were first reported in 2014 …

[HTML][HTML] Characteristics of patients with acute flaccid myelitis, United States, 2015–2018

N McLaren, A Lopez, S Kidd, J Zhang… - Emerging Infectious …, 2020 - ncbi.nlm.nih.gov
Observed peaks of acute flaccid myelitis (AFM) cases have occurred biennially since 2014
in the United States. We aimed to determine if AFM etiology differed between peak and …

Global prevalence and case fatality rate of Enterovirus D68 infections, a systematic review and meta-analysis

A Fall, S Kenmoe, JT Ebogo-Belobo… - PLoS Neglected …, 2022 - journals.plos.org
A substantial amount of epidemiological data has been reported on Enterovirus D68 (EV-
D68) infections after the 2014 outbreak. Our goal was to map the case fatality rate (CFR) and …

[HTML][HTML] Vital signs: clinical characteristics of patients with confirmed acute flaccid myelitis, United States, 2018

S Kidd - MMWR. Morbidity and Mortality Weekly Report, 2020 - cdc.gov
Background: Acute flaccid myelitis (AFM) is a serious neurologic syndrome that affects
mostly children and is characterized by the acute onset of limb weakness or paralysis. Since …

Enterovirus infection and acute flaccid myelitis

P Uprety, EH Graf - Current opinion in virology, 2020 - Elsevier
Recent outbreaks of limb paralysis similar to poliomyelitis, termed acute flaccid myelitis
(AFM), have prompted intense investigation into potential etiology. Peaks of AFM were seen …

Cryo-EM structures reveal two distinct conformational states in a picornavirus cell entry intermediate

PNM Shah, DJ Filman, KS Karunatilaka… - PLoS …, 2020 - journals.plos.org
The virions of enteroviruses such as poliovirus undergo a global conformational change
after binding to the cellular receptor, characterized by a 4% expansion, and by the opening …

Quantification and trends of rotavirus and enterovirus in untreated sewage using reverse transcription droplet digital PCR

NM Kiulia, R Gonzalez, H Thompson, TG Aw… - Food and Environmental …, 2021 - Springer
The quantification and trends in concentrations for naturally occurring rotaviruses (RV) and
enteroviruses (EV) in untreated sewage in various wastewater systems have not often been …

Development of novel PCR assays for improved detection of enterovirus D68

T Ikuse, Y Aizawa, H Takihara, S Okuda… - Journal of clinical …, 2021 - Am Soc Microbiol
ABSTRACT Enterovirus D68 (EV-D68) causes a range of clinical manifestations, including
asthma-like illness, severe respiratory disease, and acute flaccid myelitis. EV-D68 has …