This review focuses on one family of the known cAMP receptors, the exchange proteins
directly activated by cAMP (EPACs), also known as the cAMP-regulated guanine nucleotide …

Much effort has been directed at studying the orexigenic actions of administered ghrelin and
the potential effects of the endogenous ghrelin system on food intake, food reward, body …

Aim Vitamin D deficiency in rodents negatively affects glucose-stimulated insulin secretion
(GSIS) and human epidemiological studies connect poor vitamin D status with type 2 …

The growth hormone secretagogue receptor (GHSR) has emerged as one of the most
fascinating molecules from the perspective of neuroendocrine control. GHSR is mainly …

Objective Exercise training has several well-established health benefits, including many
related to body weight, appetite control, and blood glucose homeostasis. However, the …

Ghrelin is an orexigenic gastric peptide hormone secreted when caloric intake is limited.
Ghrelin also regulates blood glucose, as emphasized by the hypoglycemia that is induced …

The current study examined potential mechanisms for altered circulating ghrelin levels
observed in diet-induced obesity (DIO) and following weight loss resulting from Roux-en-Y …

Cancer remains a global health problem and approximately 1.7 million new cancer cases
are diagnosed every year worldwide. Although diverse molecules are currently being …

To determine the comprehensive G protein-coupled receptor (GPCR) expression profile in
ghrelin-producing cells and to elucidate the role of GPCR-mediated signaling in the …

The ghrelin system is a key component of the mood and metabolic responses to chronic
psychosocial stress. For example, circulating acyl-ghrelin rises in several rodent and human …