Emerging biology of noncoding RNAs in malaria parasites

K Simantov, M Goyal, R Dzikowski - PLoS pathogens, 2022 - journals.plos.org
In eukaryotic organisms, noncoding RNAs (ncRNAs) have been implicated as important
regulators of multifaceted biological processes, including transcriptional, posttranscriptional …

Navigating clinical utilization of direct-from-specimen metagenomic pathogen detection: clinical applications, limitations, and testing recommendations

LM Filkins, AL Bryson, SA Miller, SL Mitchell - Clinical chemistry, 2020 - academic.oup.com
Background Metagenomic next generation sequencing (mNGS) is becoming increasingly
available for pathogen detection directly from clinical specimens. These tests use target …

Pathogen genomics in public health

GL Armstrong, DR MacCannell, J Taylor… - … England Journal of …, 2019 - Mass Medical Soc
Rapid advances in DNA sequencing technology (“next-generation sequencing”) have
inspired optimism about the potential of human genomics for “precision medicine.” …

[PDF][PDF] Effects of microclimatic changes caused by deforestation on the survivorship and reproductive fitness of Anopheles gambiae in western Kenya highlands

YA Afrane, G Zhou, BW Lawson… - American Journal of …, 2006 - academia.edu
Land use changes have been suggested as one of the causes for malaria epidemics in the
African highlands. This study investigated the effects of deforestation-induced changes in …

Prevalence of Plasmodium falciparum field isolates with deletions in histidine-rich protein 2 and 3 genes in context with sub-Saharan Africa and India: a systematic …

LP Kojom, V Singh - Malaria journal, 2020 - Springer
Abstract Background In 2017, nearly 80% of malaria morbidity and mortality occurred in sub-
Saharan African (SSA) countries and India. Rapid diagnostic tests (RDTs), especially those …

Amplicon deep sequencing of five highly polymorphic markers of Plasmodium falciparum reveals high parasite genetic diversity and moderate population structure in …

AG Reda, T Huwe, C Koepfli, A Assefa, SK Tessema… - Malaria Journal, 2023 - Springer
Background Plasmodium falciparum genetic diversity can add information on transmission
intensity and can be used to track control and elimination interventions. Methods Dried …

Genetic diversity and allele frequencies of Plasmodium falciparum msp1 and msp2 in parasite isolates from Bioko Island, Equatorial Guinea

JT Chen, J Li, GC Zha, G Huang, ZX Huang, DD Xie… - Malaria journal, 2018 - Springer
Background Malaria is still a serious public health problem on Bioko Island (Equatorial
Guinea), although the number of annual cases has been greatly reduced since 2004 …

Plasmodium falciparum population structure inferred by msp1 amplicon sequencing of parasites collected from febrile patients in Kenya

B Andika, V Mobegi, K Gathii, J Nyataya, N Maina… - Malaria Journal, 2023 - Springer
Background Multiplicity of infection (MOI) is an important measure of Plasmodium falciparum
diversity, usually derived from the highly polymorphic genes, such as msp1, msp2 and glurp …

High-throughput genotyping of Plasmodium vivax in the Peruvian Amazon via molecular inversion probes

ZR Popkin-Hall, K Niaré, R Crudale, A Simkin… - Nature …, 2024 - nature.com
Plasmodium vivax transmission occurs throughout the tropics and is an emerging threat in
areas of Plasmodium falciparum decline, causing relapse infections that complicate …

Elucidating cryptic dynamics of Theileria communities in African buffalo using a high‐throughput sequencing informatics approach

CK Glidden, AV Koehler, RS Hall… - Ecology and …, 2020 - Wiley Online Library
Increasing access to next‐generation sequencing (NGS) technologies is revolutionizing the
life sciences. In disease ecology, NGS‐based methods have the potential to provide higher …