Janus kinase-targeting therapies in rheumatology: a mechanisms-based approach
The four Janus kinase (JAK) proteins and seven signal transducer and activator of
transcription (STAT) transcription factors mediate intracellular signal transduction …
transcription (STAT) transcription factors mediate intracellular signal transduction …
Axial spondyloarthritis
V Navarro-Compán, A Sepriano… - Annals of the …, 2021 - ard.bmj.com
Axial spondyloarthritis (axSpA) encompasses both radiographic and non-radiographic
axSpA. It is a chronic inflammatory disease with a predilection for involving the axial …
axSpA. It is a chronic inflammatory disease with a predilection for involving the axial …
The global, regional, and national burden of psoriasis: results and insights from the global burden of disease 2019 study
G Damiani, NL Bragazzi, C Karimkhani Aksut… - Frontiers in …, 2021 - frontiersin.org
Background: Psoriasis is a common, chronic, inflammatory, debilitating, systemic disease
with a great impact on healthcare systems worldwide. As targeted therapies have …
with a great impact on healthcare systems worldwide. As targeted therapies have …
Ankylosing spondylitis: an autoimmune or autoinflammatory disease?
Ankylosing spondylitis (AS) is a chronic inflammatory disorder of unknown aetiology. Unlike
other systemic autoimmune diseases, in AS, the innate immune system has a dominant role …
other systemic autoimmune diseases, in AS, the innate immune system has a dominant role …
EULAR recommendations for the management of psoriatic arthritis with pharmacological therapies: 2019 update
L Gossec, X Baraliakos, A Kerschbaumer… - Annals of the …, 2020 - ard.bmj.com
Objective To update the European League Against Rheumatism (EULAR) recommendations
for the pharmacological treatment of psoriatic arthritis (PsA). Methods According to the …
for the pharmacological treatment of psoriatic arthritis (PsA). Methods According to the …
Behçet syndrome: a contemporary view
H Yazici, E Seyahi, G Hatemi, Y Yazici - Nature Reviews Rheumatology, 2018 - nature.com
The presence of symptom clusters, regional differences in disease expression and
similarities with, for example, Crohn's disease suggest multiple pathological pathways are …
similarities with, for example, Crohn's disease suggest multiple pathological pathways are …
Axial spondyloarthritis: new advances in diagnosis and management
C Ritchlin, IE Adamopoulos - Bmj, 2021 - bmj.com
Axial spondyloarthritis (axSpA) is an inflammatory disease of the axial skeleton associated
with significant pain and disability. Previously, the diagnosis of ankylosing spondylitis …
with significant pain and disability. Previously, the diagnosis of ankylosing spondylitis …
Efficacy and safety of biologics for psoriasis and psoriatic arthritis and their impact on comorbidities: a literature review
M Kamata, Y Tada - International journal of molecular sciences, 2020 - mdpi.com
Psoriasis is a chronic inflammatory skin disease characterized by scaly indurated erythema.
It impairs patients' quality of life enormously. It has been recognized not only as a skin …
It impairs patients' quality of life enormously. It has been recognized not only as a skin …
[HTML][HTML] T helper 2 IL-4/IL-13 dual blockade with dupilumab is linked to some emergent T helper 17‒type diseases, including seronegative arthritis and enthesitis …
Dupilumab, an IL-4/IL-13 receptor blocker, has been linked to emergent seronegative
inflammatory arthritis and psoriasis that form part of the spondyloarthropathy spectrum. We …
inflammatory arthritis and psoriasis that form part of the spondyloarthropathy spectrum. We …
The role of IL-17A in axial spondyloarthritis and psoriatic arthritis: recent advances and controversies
DG McGonagle, IB McInnes, BW Kirkham… - Annals of the …, 2019 - ard.bmj.com
Although the pathogenic mechanisms underlying axial spondyloarthritis (axSpA) and
psoriatic arthritis (PsA) are not fully elucidated, several lines of evidence suggest that …
psoriatic arthritis (PsA) are not fully elucidated, several lines of evidence suggest that …