In the past 25 years, genetic and biochemical analyses of ribosome assembly in yeast have
identified most of the factors that participate in this complex pathway and have generated …

Eukaryotic ribosome synthesis is a complex, energy-consuming process that takes place
across the nucleolus, nucleoplasm and cytoplasm and requires more than 200 conserved …

The biogenesis of eukaryotic ribosomes is a complicated process during which the
transcription, modification, folding, and processing of the rRNA is coupled with the ordered …

Eukaryotic small ribosomal subunits are first assembled into 90S pre-ribosomes. The
complete 90S is a gigantic complex with a molecular mass of approximately five …

The coordinated integration of ribosomal RNA and protein into two functional ribosomal
subunits is safeguarded by quality control checkpoints that ensure ribosomes are correctly …

The formation of eukaryotic ribosomal subunits extends from the nucleolus to the cytoplasm
and entails hundreds of assembly factors. Despite differences in the pathways of ribosome …

INTRODUCTION The eukaryotic ribosome is assembled through an intricate process that
involves in excess of 250 nonribosomal proteins and small nucleolar RNAs (snoRNAs) …

The 40S small ribosomal subunit is cotranscriptionally assembled in the nucleolus as part of
a large chaperone complex called the 90S preribosome or small-subunit processome. Here …

Final maturation of eukaryotic ribosomes occurs in the cytoplasm and requires the
sequential removal of associated assembly factors and processing of the immature 20S pre …

Mechanistic understanding of eukaryotic ribosome formation requires a detailed structural
knowledge of the numerous assembly intermediates, generated along a complex pathway …