Asthma is a complex respiratory disorder characterized by marked heterogeneity in
individual patient disease triggers and response to therapy. Several asthma phenotypes …

The gastrointestinal epithelium forms the boundary between the body and external
environment. It effectively provides a selective permeable barrier that limits the permeation …

Asthma is characterised by heterogeneous clinical phenotypes. Our objective was to
determine molecular phenotypes of asthma by analysing sputum cell transcriptomics from …

Background Asthma is heterogeneous, and airway dysbiosis is associated with clinical
features in patients with mild-to-moderate asthma. Whether similar relationships exist among …

Allergic diseases are on the rise in the Western world and well-known allergy-protecting and-
driving factors such as microbial and dietary exposure, pollution and smoking mediate their …

Curcumin is a dietary polyphenol from turmeric with numerous pharmacological activities.
Novel animal and human studies indicate that curcumin can affect different immune cells …

The discovery of IgE represented a major breakthrough in allergy and asthma research,
whereas the clinical interest given to IgE in asthma has been blurred until the arrival of anti …

The lung is the organ with the highest vascular density in the human body. It is therefore
perceivable that the endothelium of the lung contributes significantly to the circulation of …

Eosinophils derive from the bone marrow and circulate at low levels in the blood in healthy
individuals. These granulated cells preferentially leave the circulation and marginate to …

AIM To investigate whether immune mediated diseases (IMD) are more frequent in patients
with inflammatory bowel disease (IBD). METHODS In this population based registry study, a …