Osmosis, from molecular insights to large-scale applications
Osmosis is a universal phenomenon occurring in a broad variety of processes and fields. It
is the archetype of entropic forces, both trivial in its fundamental expression–the van't Hoff …
is the archetype of entropic forces, both trivial in its fundamental expression–the van't Hoff …
[PDF][PDF] The ascending pathophysiology of cholestatic liver disease
In this review we develop the argument that cholestatic liver diseases, particularly primary
biliary cholangitis and primary sclerosing cholangitis (PSC), evolve over time with …
biliary cholangitis and primary sclerosing cholangitis (PSC), evolve over time with …
Tight junctions control lumen morphology via hydrostatic pressure and junctional tension
M Mukenhirn, CH Wang, T Guyomar, MJ Bovyn… - Developmental Cell, 2024 - cell.com
Formation of fluid-filled lumina by epithelial tissues is essential for organ development. How
cells control the hydraulic and cortical forces to control lumen morphology is not well …
cells control the hydraulic and cortical forces to control lumen morphology is not well …
Bioelectric stimulation controls tissue shape and size
Epithelial tissues sheath organs and electro-mechanically regulate ion and water transport
to regulate development, homeostasis, and hydrostatic organ pressure. Here, we …
to regulate development, homeostasis, and hydrostatic organ pressure. Here, we …
FIP 5 phosphorylation during mitosis regulates apical trafficking and lumenogenesis
D Li, A Mangan, L Cicchini, B Margolis, R Prekeris - EMBO reports, 2014 - embopress.org
Apical lumen formation is a key step during epithelial morphogenesis. The establishment of
the apical lumen is a complex process that involves coordinated changes in plasma …
the apical lumen is a complex process that involves coordinated changes in plasma …
[HTML][HTML] Tissue hydraulics: physics of lumen formation and interaction
Lumen formation plays an essential role in the morphogenesis of tissues during
development. Here we review the physical principles that play a role in the growth and …
development. Here we review the physical principles that play a role in the growth and …
Collective epithelial cell invasion overcomes mechanical barriers of collagenous extracellular matrix by a narrow tube-like geometry and MMP14-dependent local …
Collective cell invasion (CCI) through interstitial collagenous extracellular matrix (ECM) is
crucial to the initial stages of branching morphogenesis, and a hallmark of tissue repair and …
crucial to the initial stages of branching morphogenesis, and a hallmark of tissue repair and …
Using Microfluidics to Align Matrix Architecture and Generate Chemokine Gradients Promotes Directional Branching in a Model of Epithelial Morphogenesis
JY Lichtenberg, CE Leonard, HR Sterling… - ACS Biomaterials …, 2024 - ACS Publications
The mechanical cue of fiber alignment plays a key role in the development of various tissues
in the body. The ability to study the effect of these stimuli in vitro has been limited previously …
in the body. The ability to study the effect of these stimuli in vitro has been limited previously …
Computational approaches for simulating luminogenesis
Lumens, liquid-filled cavities surrounded by polarized tissue cells, are elementary units
involved in the morphogenesis of organs. Theoretical modeling and computations, which …
involved in the morphogenesis of organs. Theoretical modeling and computations, which …
Tight junctions regulate lumen morphology via hydrostatic pressure and junctional tension
Formation of fluid filled lumen by epithelial tissues is a fundamental process for organ
development. How epithelial cells regulate the hydraulic and cortical forces to control lumen …
development. How epithelial cells regulate the hydraulic and cortical forces to control lumen …