[HTML][HTML] The limitless future of RNA therapeutics

TR Damase, R Sukhovershin, C Boada… - … in bioengineering and …, 2021 - frontiersin.org
Recent advances in the generation, purification and cellular delivery of RNA have enabled
development of RNA-based therapeutics for a broad array of applications. RNA therapeutics …

Emerging concepts and technologies in vaccine development

M Brisse, SM Vrba, N Kirk, Y Liang, H Ly - Frontiers in immunology, 2020 - frontiersin.org
Despite the success of vaccination to greatly mitigate or eliminate threat of diseases caused
by pathogens, there are still known diseases and emerging pathogens for which the …

New vaccine technologies to combat outbreak situations

S Rauch, E Jasny, KE Schmidt, B Petsch - Frontiers in immunology, 2018 - frontiersin.org
Ever since the development of the first vaccine more than 200 years ago, vaccinations have
greatly decreased the burden of infectious diseases worldwide, famously leading to the …

Frequency and associations of adverse reactions of COVID-19 vaccines reported to pharmacovigilance systems in the European Union and the United States

D Montano - Frontiers in public health, 2022 - frontiersin.org
Introduction This study aims to provide a risk assessment of the adverse reactions related to
the COVID-19 vaccines manufactured by AstraZeneca, Janssen, Moderna, and Pfizer …

Rise of the RNA machines–self-amplification in mRNA vaccine design

JDG Comes, GP Pijlman, TAH Hick - Trends in Biotechnology, 2023 - cell.com
Abstract mRNA vaccines have won the race for early COVID-19 vaccine approval, yet
improvements are necessary to retain this leading role in combating infectious diseases. A …

The current status, challenges, and future developments of new tuberculosis vaccines

W Gong, Y Liang, X Wu - Human vaccines & immunotherapeutics, 2018 - Taylor & Francis
Mycobacterium tuberculosis complex causes tuberculosis (TB), one of the top 10 causes of
death worldwide. TB results in more fatalities than multi-drug resistant (MDR) HIV strain …

A perspective on current flavivirus vaccine development: a brief review

SK Dutta, T Langenburg - Viruses, 2023 - mdpi.com
The flavivirus genus contains several clinically important pathogens that account for
tremendous global suffering. Primarily transmitted by mosquitos or ticks, these viruses can …

COVID‐19: Clinical status of vaccine development to date

S Kumar, M Basu, P Ghosh, A Ansari… - British Journal of …, 2023 - Wiley Online Library
Severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2)‐induced COVID‐19 is a
complicated disease. Clinicians are continuously facing difficulties to treat infected patients …

COVID-19 vaccine platforms: Delivering on a promise?

M Verdecia, JF Kokai-Kun, M Kibbey… - Human vaccines & …, 2021 - Taylor & Francis
The emergence of the novel SARS-CoV-2 and COVID-19 has brought into sharp focus the
need for a vaccine to prevent this disease. Vaccines have saved millions of lives since their …

Vaccine development: Current trends and technologies

R Poria, D Kala, R Nagraik, Y Dhir, S Dhir, B Singh… - Life Sciences, 2023 - Elsevier
Despite the effectiveness of vaccination in reducing or eradicating diseases caused by
pathogens, there remain certain diseases and emerging infections for which developing …