Artificial intelligence: Machine learning approach for screening large database and drug discovery
PP Parvatikar, S Patil, K Khaparkhuntikar, S Patil… - Antiviral Research, 2023 - Elsevier
Recent research in drug discovery dealing with many faces difficulties, including
development of new drugs during disease outbreak and drug resistance due to rapidly …
development of new drugs during disease outbreak and drug resistance due to rapidly …
Indole–a promising pharmacophore in recent antiviral drug discovery
A Dorababu - RSC Medicinal Chemistry, 2020 - pubs.rsc.org
The bicyclic molecule indole has been in the limelight because of its numerous
pharmacological potencies. It is used as an excellent scaffold in drug discovery of medicinal …
pharmacological potencies. It is used as an excellent scaffold in drug discovery of medicinal …
Basic concepts in population modeling, simulation, and model‐based drug development: part 3—introduction to pharmacodynamic modeling methods
RN Upton, DR Mould - CPT: pharmacometrics & systems …, 2014 - Wiley Online Library
Population pharmacodynamic (PD) models describe the time course of drug effects, relating
exposure to response, and providing a more robust understanding of drug action than single …
exposure to response, and providing a more robust understanding of drug action than single …
Cost-effectiveness of non-invasive methods for assessment and monitoring of liver fibrosis and cirrhosis in patients with chronic liver disease: systematic review and …
BACKGROUND: Liver biopsy is the reference standard for diagnosing the extent of fibrosis
in chronic liver disease; however, it is invasive, with the potential for serious complications …
in chronic liver disease; however, it is invasive, with the potential for serious complications …
Unboxing the molecular modalities of mutagens in cancer
The etiology of the majority of human cancers is associated with a myriad of environmental
causes, including physical, chemical, and biological factors. DNA damage induced by such …
causes, including physical, chemical, and biological factors. DNA damage induced by such …
[HTML][HTML] Overview of hepatitis C infection, molecular biology, and new treatment
AA Rabaan, SH Al-Ahmed, AM Bazzi… - Journal of infection and …, 2020 - Elsevier
Abstract The World Health Organization estimates that 71 million people worldwide have
chronic hepatitis C viral infection. A major challenge is overall lack of public awareness of …
chronic hepatitis C viral infection. A major challenge is overall lack of public awareness of …
Mathematical and computational techniques for drug discovery: promises and developments
K Balasubramanian - Current Topics in Medicinal Chemistry, 2018 - ingentaconnect.com
We review various mathematical and computational techniques for drug discovery
exemplifying some recent works pertinent to group theory of nested structures of relevance …
exemplifying some recent works pertinent to group theory of nested structures of relevance …
Recent patents and FDA-approved drugs based on antiviral peptides and other peptide-related antivirals
MS Mousavi Maleki, S Sardari… - International Journal of …, 2022 - Springer
In spite of existing cases of severe viral infections with a high mortality rate, there are not
enough antiviral drugs and vaccines available for the prevention and treatment of such …
enough antiviral drugs and vaccines available for the prevention and treatment of such …
DRAVP: a comprehensive database of antiviral peptides and proteins
Y Liu, Y Zhu, X Sun, T Ma, X Lao, H Zheng - Viruses, 2023 - mdpi.com
Viruses with rapid replication and easy mutation can become resistant to antiviral drug
treatment. With novel viral infections emerging, such as the recent COVID-19 pandemic …
treatment. With novel viral infections emerging, such as the recent COVID-19 pandemic …
Recent patents and FDA-approved drugs based on antiviral peptides and other peptide-related antivirals
MSM Maleki, S Sardari, AG Alavijeh… - … journal of peptide …, 2022 - pmc.ncbi.nlm.nih.gov
In spite of existing cases of severe viral infections with a high mortality rate, there are not
enough antiviral drugs and vaccines available for the prevention and treatment of such …
enough antiviral drugs and vaccines available for the prevention and treatment of such …