The direct targets of metformin in diabetes and beyond
L Yao, L Wang, R Zhang, AA Soukas, L Wu - Trends in Endocrinology & …, 2024 - cell.com
Metformin, an oral antihyperglycemic drug that has been in use for over 60 years, remains a
first-line therapy for type 2 diabetes (T2D). Numerous studies have suggested that metformin …
first-line therapy for type 2 diabetes (T2D). Numerous studies have suggested that metformin …
Current type 2 diabetes guidelines: Individualized treatment and how to make the most of metformin
Evidence‐based guidelines provide the premise for the delivery of quality care to preserve
health and prevent disabilities and premature death. The systematic gathering of …
health and prevent disabilities and premature death. The systematic gathering of …
Nutrition at the Intersection between Gut Microbiota Eubiosis and Effective Management of Type 2 Diabetes
Nutrition is one of the most influential environmental factors in both taxonomical shifts in gut
microbiota as well as in the development of type 2 diabetes mellitus (T2DM). Emerging …
microbiota as well as in the development of type 2 diabetes mellitus (T2DM). Emerging …
PM2.5 induced neurotoxicity through unbalancing vitamin B12 metabolism by gut microbiota disturbance
X Zhu, Y Xia, H Wang, L Shi, H Yin, M Gu, F Yan - Gut Microbes, 2023 - Taylor & Francis
ABSTRACT Fine particulate matter (PM2. 5) in the atmosphere is easily accompanied by
toxic and harmful substances, causing serious harm to human health, including cognitive …
toxic and harmful substances, causing serious harm to human health, including cognitive …
Synergistic effects of quaternary ammonium compounds and antibiotics on the evolution of antibiotic resistance
P Wang, H Wang, S Qi, W Wang, H Lu - Water Research, 2025 - Elsevier
The usage of quaternary ammonium compounds (QACs) as disinfectants has surged
dramatically during the COVID-19 pandemic and thereafter. QACs can promote …
dramatically during the COVID-19 pandemic and thereafter. QACs can promote …
Caenorhabditis elegans as a Convenient Animal Model for Microbiome Studies
CY Wu, S Davis, N Saudagar, S Shah, W Zhao… - International Journal of …, 2024 - mdpi.com
Microbes constitute the most prevalent life form on Earth, yet their remarkable diversity
remains mostly unrecognized. Microbial diversity in vertebrate models presents a significant …
remains mostly unrecognized. Microbial diversity in vertebrate models presents a significant …
[PDF][PDF] Effect of metformin on vitamin B12 and homocysteine levels among Sudanese with type 2 diabetes mellitus
SMA Al-Ghaili, EMA Tayrab, EI Obeagu - Elite Journal of Medicine, 2024 - researchgate.net
Metformin is the first-line treatment for type 2 diabetes mellitus (T2DM), and hyperglycemia.
When taken in high doses or for an extended period, metformin may decrease vitamin B12 …
When taken in high doses or for an extended period, metformin may decrease vitamin B12 …