Current perspectives on Stevens-Johnson syndrome and toxic epidermal necrolysis

M Lerch, C Mainetti, B Terziroli Beretta-Piccoli… - Clinical reviews in …, 2018 - Springer
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are considered a
delayed-type hypersensitivity reaction to drugs. They represent true medical emergencies …

An updated review of the molecular mechanisms in drug hypersensitivity

CB Chen, R Abe, RY Pan, CW Wang… - Journal of …, 2018 - Wiley Online Library
Drug hypersensitivity may manifest ranging from milder skin reactions (eg, maculopapular
exanthema and urticaria) to severe systemic reactions, such as anaphylaxis, drug reactions …

Drug-induced hypersensitivity syndrome (DIHS)/drug reaction with eosinophilia and systemic symptoms (DRESS): clinical features and pathogenesis

N Hama, R Abe, A Gibson, EJ Phillips - The Journal of Allergy and Clinical …, 2022 - Elsevier
Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic
symptoms (DIHS/DRESS) is one example of a severe delayed T-cell–mediated adverse …

[HTML][HTML] Recent advances in managing and understanding Stevens-Johnson syndrome and toxic epidermal necrolysis

A Hasegawa, R Abe - F1000Research, 2020 - ncbi.nlm.nih.gov
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening
diseases characterized by detachment of the epidermis and mucous membrane. SJS/TEN …

The role of pharmacogenomics in adverse drug reactions

R Cacabelos, N Cacabelos, JC Carril - Expert Review of Clinical …, 2019 - Taylor & Francis
ABSTRACT Introduction: Adverse drug reactions (ADRs) are a major health concern
worldwide. There are multiple causes of ADRs, some of which are preventable …

Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms. Part I. Epidemiology, pathogenesis, clinicopathological features, and …

BM Wei, LP Fox, BH Kaffenberger, AM Korman… - Journal of the American …, 2024 - Elsevier
Drug-induced hypersensitivity syndrome (DiHS), also known as drug reaction with
eosinophilia and systemic symptoms (DRESS), is a severe cutaneous adverse reaction …

Drug reaction with eosinophilia and systemic symptoms (DReSS)/Drug-Induced hypersensitivity syndrome (DiHS)—readdressing the DReSS

H Stirton, NH Shear, RP Dodiuk-Gad - Biomedicines, 2022 - mdpi.com
Drug reaction with eosinophilia and systemic symptoms (DReSS), also known as drug-
induced hypersensitivity syndrome (DiHS), is a severe, systemic, T cell mediated drug …

[HTML][HTML] Novel genetic and epigenetic factors of importance for inter-individual differences in drug disposition, response and toxicity

VM Lauschke, Y Zhou, M Ingelman-Sundberg - Pharmacology & …, 2019 - Elsevier
Individuals differ substantially in their response to pharmacological treatment. Personalized
medicine aspires to embrace these inter-individual differences and customize therapy by …

An updated review of genetic associations with severe adverse drug reactions: Translation and implementation of pharmacogenomic testing in clinical practice

CW Wang, IAC Preclaro, WH Lin… - Frontiers in …, 2022 - frontiersin.org
Adverse drug reactions (ADR) remain the major problems in healthcare. Most severe ADR
are unpredictable, dose-independent and termed as type B idiosyncratic reactions. Recent …

Drug reaction with eosinophilia and systemic symptoms (DRESS): focus on the pathophysiological and diagnostic role of viruses

GA Ramirez, M Ripa, S Burastero, G Benanti… - Microorganisms, 2023 - mdpi.com
Drug reaction with eosinophilia and systemic symptoms (DRESS) is a heterogeneous,
multiorgan and potentially life-threatening drug-hypersensitivity reaction (DHR) that occurs …