The blood–brain barrier (BBB) is an important physiological barrier that separates the
central nervous system (CNS) from the peripheral circulation, which contains inflammatory …

The central nervous system can respond to threat via the induction of an inflammatory
response. Under normal circumstances this response is tightly controlled, however …

The intricate relationships between innate immunity and brain diseases raise increased
interest across the wide spectrum of neurodegenerative and neuropsychiatric disorders …

Mast cell activation plays an important role in stress-mediated disease pathogenesis.
Chronic stress cause or exacerbate aging and age-dependent neurodegenerative diseases …

Age-related hearing loss, or presbycusis, is a common cause of hearing loss in elderly
people worldwide. It typically presents as progressive, irreversible, and usually affects the …

The blood–brain barrier (BBB) plays a vital role in maintaining the specialized
microenvironment of the brain tissue. It facilitates communication while separating the …

Most neurological disorders seemingly have heterogenous pathogenesis, with overlapping
contribution of neuronal, immune and vascular mechanisms of brain injury. The perivascular …

Astroglia or astrocytes, the most abundant cells in the brain, are interposed between
neuronal synapses and microvasculature in the brain gray matter. They play a pivotal role in …

Redox-active, strongly magnetic, combustion and friction-derived nanoparticles (CFDNPs)
are abundant in particulate matter air pollution. Urban children and young adults with …

Glioblastoma (GBM), an aggressive high-grade glial tumor, is resistant to therapy and has a
poor prognosis due to its universal recurrence rate. GBM cells interact with the non-cellular …