Pneumonia is a type of acute lower respiratory infection that is common and severe. The
outcome of lower respiratory infection is determined by the degrees to which immunity is …

Lung disease encompasses acute, infectious processes and chronic, non-infectious
processes such as chronic obstructive pulmonary disease, asthma and lung cancer. People …

Background The lung microbiome of healthy individuals frequently harbors oral organisms.
Despite evidence that microaspiration is commonly associated with smoking-related lung …

Despite anti-retroviral therapy (ART), human immunodeficiency virus-1 (HIV)-related
pulmonary disease continues to be a major cause of morbidity and mortality for people living …

The predisposition of cigarette smokers for development of oral and respiratory infections
caused by microbial pathogens is well recognised, with those infected with the human …

Monocytes and macrophages play critical roles in HIV transmission, viral spread early in
infection, and as a reservoir of virus throughout infection. There has been a recent …

Pneumonia is very common and continues to exact a high burden on health. The Global
Burden of Disease Study 2015 found lower respiratory infections (LRIs) were the leading …

Despite the success of antiretroviral therapy (ART), people living with HIV continue to suffer
from high burdens of respiratory infections, lung cancers and chronic lung disease at a …

The widespread use of combination antiretroviral therapies (cART) has converted the
prognosis of HIV infection from a rapidly progressive and ultimately fatal disease to a chronic …

The development of culture-independent techniques has revolutionized our understanding
of how our human cells interact with the even greater number of microbial inhabitants of our …