Deciphering the secret of successful aging depends on understanding the patterns and
biological underpinnings of cognitive and behavioral changes throughout adulthood. That …

Stroke is the second most common cause of global death following coronary artery disease.
Time is crucial in managing stroke to reduce the rapidly progressing insult of the ischemic …

Hippocampal atrophy (HA) is usually attributed to the neurofibrillary tangles and neuritic
plaques of Alzheimer disease. However, the hippocampus is vulnerable to global ischemia …

Nimodipine is a 1, 4-dihydropyridine-derivative Ca2+-channel blocker developed
approximately 30 years ago. It is highly lipophilic, crosses the blood-brain barrier, and …

The brain is typically considered a target for late stage hypertensive disease due to the high
prevalence of stroke among hypertensive patients. Research is reviewed, however, that …

Arterial hypertension is the main risk factor for stroke and plays a role in the development of
vascular cognitive impairment (VCI) and vascular dementia (VaD). An association between …

Evidence suggests that obesity adversely affects brain function. High body mass index,
hypertension, dyslipidemia, insulin resistance, and diabetes are risk factors for increasing …

Hypertension is an important risk factor for cerebrovascular disease including stroke and
has also a role in the development of vascular cognitive impairment (VCI) and vascular …

The present study was designed to assess if treatment with acetylcholinesterase inhibitor
galantamine and the cholinergic precursor choline alphoscerate (alpha-glyceryl-phosphoryl …

Metabolic syndrome (MetS) is an association between obesity, dyslipidemia, hyperglycemia,
hypertension, and insulin resistance. A relationship between MetS and vascular dementia …