Inflammasomes are large protein complexes that play a major role in sensing inflammatory
signals and triggering the innate immune response. Each inflammasome complex has three …

There is an increasing prevalence of Vascular Cognitive Impairment (VCI) worldwide, and
several studies have suggested that Chronic Cerebral Hypoperfusion (CCH) plays a critical …

SARM1 (sterile alpha and TIR motif containing 1) is responsible for depletion of
nicotinamide adenine dinucleotide in its oxidized form (NAD+) during Wallerian …

The inflammasome is a three-component (sensor, adaptor, and effector) filamentous
signaling platform that shields from multiple pathogenic infections by stimulating the …

Nucleotide-binding and leucine-rich repeat (NLR) proteins are critical intracellular immune
receptors in both animals and plants. Perception of pathogen-derived or stress-associated …

Plant and animal intracellular nucleotide-binding, leucine-rich repeat (NLR) immune
receptors detect pathogen-derived molecules and activate defense. Plant NLRs can be …

NLRP1 and CARD8 are related cytosolic sensors that upon activation form supramolecular
signalling complexes known as canonical inflammasomes, resulting in caspase− 1 …

Nod-like receptor (NLR) proteins activate pyroptotic cell death and IL-1 driven inflammation
by assembling and activating the inflammasome complex. Closely related sensor proteins …

Structural Insights into the Plant Immune Receptors PRRs and NLRs1 [OPEN] | Plant
Physiology | Oxford Academic Skip to Main Content Advertisement Oxford Academic …

The inflammasome is a multi-protein platform that assembles upon the presence of cues
derived from infection or tissue damage, and triggers the inflammatory response …