Many research questions in fields such as personalized medicine, drug screens or systems
biology depend on obtaining consistent and quantitatively accurate proteomics data from …

The recent development of machine learning methods to identify peptides in complex mass
spectrometric data constitutes a major breakthrough in proteomics. Longstanding methods …

This review provides a brief overview of the development of data‐independent acquisition
(DIA) mass spectrometry‐based proteomics and selected DIA data analysis tools. Various …

Data independent acquisition (DIA) mass spectrometry is a powerful technique that is
improving the reproducibility and throughput of proteomics studies. Here, we introduce an …

Quantitative proteomics employing mass spectrometry is an indispensable tool in life
science research. Targeted proteomics has emerged as a powerful approach for …

The ultimate aim of proteomics is to fully identify and quantify the entire complement of
proteins and post-translational modifications in biological samples of interest. For the last 15 …

Liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) is the main
method for high-throughput identification and quantification of peptides and inferred …

Data-independent acquisition (DIA) mass spectrometry (MS) has emerged as a powerful
technology for high-throughput, accurate, and reproducible quantitative proteomics. This …

Bioinformatics has played an important role in analyzing chemical information acquired
using mass spectrometry (MS) for large numbers of biological samples. Here we review the …

Recent advances in commercial mass spectrometers with higher resolving power and faster
scanning capabilities have expanded their functionality beyond traditional data-dependent …