This chapter provides a comprehensive overview of malignant gliomas, the most common
primary brain tumor in adults. These tumors are varied in their cellular origin, genetic profile …

Malignant gliomas, the most common type of primary brain tumor in adults, are associated
with disproportionate cancer-related morbidity and mortality. Recently, there have been …

Standard methods for meta‐analysis are limited to pooling tasks in which a single effect size
is estimated from a set of independent studies. However, this setting can be too restrictive for …

Malignant astrocytic gliomas such as glioblastoma are the most common and lethal
intracranial tumors. These cancers exhibit a relentless malignant progression characterized …

The term “brain tumor” refers to a collection of neoplasms, each with its own biology,
prognosis, and treatment; these tumors are better identified as “intracranial neoplasms,” …

A previous placebo-controlled trial has shown that biodegradable 1, 3-bis (2-chloroethyl)-1-
nitrosourea (BCNU) wafers (Gliadel wafers) prolong survival in patients with recurrent …

The median survival of glioblastoma patients is∼ 12 months. However, 3–5% of the patients
survives for more than 3 years and are referred to as long-term survivors. The clinical and …

Malignant gliomas such as glioblastoma multiforme (GBM) present some of the greatest
challenges in the management of cancer patients worldwide, despite notable recent …

Background & Aims We performed a meta-analysis of individual patient data from 11
randomized controlled trials comparing corticosteroids, pentoxifylline, or their combination in …

We aimed to evaluate the feasibility and tolerability of the newly developed thermotherapy
using magnetic nanoparticles on recurrent glioblastoma multiforme. Fourteen patients …