Glial fibrillary acidic protein (GFAP), a type III intermediate filament, is a marker of mature
astrocytes. The expression of GFAP gene is regulated by many transcription factors (TFs) …

Expression of the GFAP gene has attracted considerable attention because its onset is a
marker for astrocyte development, its upregulation is a marker for reactive gliosis, and its …

Spinal cord injury (SCI), began with a primary injury including contusion and compression, is
a common disease caused by various pathogenesis. Characterized disruption of axons and …

The pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are well-known
xenobiotic-sensing nuclear receptors with overlapping functions. However, there lacks a …

Iron deficiency (ID) anemia is the foremost micronutrient deficiency worldwide, affecting
around 40% of pregnant women and young children. ID during the prenatal and early …

Complex chromosome rearrangements (CCRs) are currently defined as structural genome
variations that involve more than 2 chromosome breaks and result in exchanges of …

Lysine-specific demethylase 4 A (KDM4A, also named JMJD2A, KIA0677, or JHDM3A) is a
demethylase that can remove methyl groups from histones H3K9me2/3, H3K36me2/3, and …

Epigenetic modifications are chemical modifications that affect gene expression without
altering DNA sequences. In particular, epigenetic chemical modifications can occur on …

Post-translational methylation of H3 lysine 36 (H3K36) is an important epigenetic marker
that majorly contributes to the functionality of the chromatin. This mark is interpreted by the …

Background: Although neonatal exposure to anesthetic drugs is associated with memory
deficiency in rodent models and possibly in pediatric patients, the underlying mechanisms …