Advances in biodegradable and injectable hydrogels for biomedical applications
Y Li, HY Yang, DS Lee - Journal of Controlled Release, 2021 - Elsevier
In situ-forming injectable hydrogels are smart biomaterials that can be implanted into living
bodies with minimal invasion. Due to pioneer work of Prof. Sung Wan Kim in this field …
bodies with minimal invasion. Due to pioneer work of Prof. Sung Wan Kim in this field …
Cancer metastasis: the role of the extracellular matrix and the heparan sulfate proteoglycan perlecan
Cancer metastasis is the dissemination of tumor cells to new sites, resulting in the formation
of secondary tumors. This process is complex and is spatially and temporally regulated by …
of secondary tumors. This process is complex and is spatially and temporally regulated by …
Polysaccharide and polypeptide based injectable thermo-sensitive hydrogels for local biomedical applications
Injectable thermo-responsive hydrogels have been studied for various biomedical
applications including; drug delivery, cell encapsulation, and tissue repairing. There are …
applications including; drug delivery, cell encapsulation, and tissue repairing. There are …
Multifunctional drug-loaded micelles encapsulated in thermo-sensitive hydrogel for in vivo local cancer treatment: Synergistic effects of anti-vascular and immuno …
Localized cancer therapy with combination of drugs is an effective treatment modality which
increase inhibition of tumor growth and reoccurrence. Recently, hydrogels that can …
increase inhibition of tumor growth and reoccurrence. Recently, hydrogels that can …
Hyaluronic acid thiol modified injectable hydrogel: Synthesis, characterization, drug release, cellular drug uptake and anticancer activity
K Xu, H Yao, D Fan, L Zhou, S Wei - Carbohydrate Polymers, 2021 - Elsevier
Dimethyl sulfoxide (DMSO) is an excellent solvent for various types of anticancer drugs.
Here, beyond that, it can participate in a disulfide bond crosslink between sulfhydryl (-SH) …
Here, beyond that, it can participate in a disulfide bond crosslink between sulfhydryl (-SH) …
Injectable hydrogels for cancer therapy over the last decade
The interest in injectable hydrogels for cancer treatment has been significantly growing over
the last decade, due to the availability of a wide range of starting polymer structures with …
the last decade, due to the availability of a wide range of starting polymer structures with …
Ibuprofen-loaded heparin modified thermosensitive hydrogel for inhibiting excessive inflammation and promoting wound healing
Hydrogels have been investigated as ideal biomaterials for wound treatment owing to their
ability to form a highly moist environment which accelerates cell migration and tissue …
ability to form a highly moist environment which accelerates cell migration and tissue …
Heparin and its derivatives: challenges and advances in therapeutic biomolecules
Heparin has been extensively studied as a safe medicine and biomolecule over the past few
decades. Heparin derivatives, including low-molecular-weight heparins (LMWH) and …
decades. Heparin derivatives, including low-molecular-weight heparins (LMWH) and …
Localized controlled release of bevacizumab and doxorubicin by thermo-sensitive hydrogel for normalization of tumor vasculature and to enhance the efficacy of …
In a malignant tumor, overexpression of pro-angiogenic factors like vascular endothelial
growth factor (VEGF) provokes the production of pathologic vascular networks characterized …
growth factor (VEGF) provokes the production of pathologic vascular networks characterized …
Fabrication of redox-responsive Bi (mPEG-PLGA)-Se2 micelles for doxorubicin delivery
YS Birhan, BZ Hailemeskel, TW Mekonnen… - International Journal of …, 2019 - Elsevier
Stimuli-responsive polymeric nanostructures have emerged as potential drug carriers for
cancer therapy. Herein, we synthesized redox-responsive diselenide bond containing …
cancer therapy. Herein, we synthesized redox-responsive diselenide bond containing …