Chemistry, biochemistry, and safety of acrylamide. A review

M Friedman - Journal of agricultural and food chemistry, 2003 - ACS Publications
Acrylamide (CH2 CH CONH2), an industrially produced α, β-unsaturated (conjugated)
reactive molecule, is used worldwide to synthesize polyacrylamide. Polyacrylamide has …

Neurotoxins affecting neuroexocytosis

G Schiavo, M Matteoli… - Physiological reviews, 2000 - journals.physiology.org
Nerve terminals are specific sites of action of a very large number of toxins produced by
many different organisms. The mechanism of action of three groups of presynaptic …

[HTML][HTML] NO as a signalling molecule in the nervous system

JV Esplugues - British journal of pharmacology, 2002 - ncbi.nlm.nih.gov
NO was first characterized in the CNS as the intercellular messenger mediating the increase
in cyclic GMP levels that follows activation of glutamate receptors (Garthwaite et al., 1988) …

Nitric oxide and neuronal death

GC Brown - Nitric oxide, 2010 - Elsevier
NO and its derivatives can have multiple effects, which impact on neuronal death in different
ways. High levels of NO induces energy depletion-induced necrosis, due to:(i) rapid …

The role of nitric oxide in pre-synaptic plasticity and homeostasis

N Hardingham, J Dachtler, K Fox - Frontiers in cellular neuroscience, 2013 - frontiersin.org
Since the observation that nitric oxide (NO) can act as an intercellular messenger in the
brain, the past 25 years have witnessed the steady accumulation of evidence that it acts pre …

[图书][B] Perceptual neuroscience: the cerebral cortex

VB Mountcastle - 1998 - books.google.com
The cerebral cortex, occupying over 70 percent of our brain mass, is key to any
understanding of the workings--and disorders--of the human brain. offering a …

(S) NO signals: translocation, regulation, and a consensus motif

JS Stamler, EJ Toone, SA Lipton, NJ Sucher - Neuron, 1997 - cell.com
Nitric oxide (NO) is a signaling molecule that has capin the immune system in work by
DeGroote and Fang tured our imagination. According to the common view,(DeGroote et al …

Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria

GC Brown, A Bal-Price - Molecular neurobiology, 2003 - Springer
In inflammatory, infectious, ischemic, and neurodegenerative pathologies of th central
nervous system (CNS) glia become “activated” by inflammatory mediators, and express new …

GRASP65, a protein involved in the stacking of Golgi cisternae

FA Barr, M Puype, J Vandekerckhove, G Warren - Cell, 1997 - cell.com
NEM prevents mitotic reassembly of Golgi cisternae into stacked structures. The major target
of NEM is a 65 kDa protein conserved from yeast to mammals. Antibodies to this protein and …

The N-methyl-D-aspartate receptor subunit NR2B: localization, functional properties, regulation, and clinical implications

JM Loftis, A Janowsky - Pharmacology & therapeutics, 2003 - Elsevier
The N-methyl-d-aspartate (NMDA) receptor is an example of a heteromeric ligand-gated ion
channel that interacts with multiple intracellular proteins by way of different subunits. NMDA …