The dynamics of the skin's immune system

AV Nguyen, AM Soulika - International journal of molecular sciences, 2019 - mdpi.com
The skin is a complex organ that has devised numerous strategies, such as physical,
chemical, and microbiological barriers, to protect the host from external insults. In addition …

Human dendritic cell subsets: an update

M Collin, V Bigley - Immunology, 2018 - Wiley Online Library
Dendritic cells (DC) are a class of bone‐marrow‐derived cells arising from lympho‐myeloid
haematopoiesis that form an essential interface between the innate sensing of pathogens …

Wound healing in aged skin exhibits systems-level alterations in cellular composition and cell-cell communication

R Vu, S Jin, P Sun, D Haensel, QH Nguyen, M Dragan… - Cell reports, 2022 - cell.com
Delayed and often impaired wound healing in the elderly presents major medical and
socioeconomic challenges. A comprehensive understanding of the cellular/molecular …

Antigen-presenting cells in the skin

SW Kashem, M Haniffa… - Annual review of …, 2017 - annualreviews.org
Professional antigen-presenting cells (APCs) in the skin include dendritic cells, monocytes,
and macrophages. They are highly dynamic, with the capacity to enter skin from the …

Langerhans cells: sensing the environment in health and disease

J Deckers, H Hammad, E Hoste - Frontiers in immunology, 2018 - frontiersin.org
In the last few decades, our understanding of Langerhans cells (LCs) has drastically
changed based on novel findings regarding the developmental origin and biological …

Inflammation: A key process in skin tumorigenesis

M Neagu, C Constantin, C Caruntu… - Oncology …, 2019 - spandidos-publications.com
The extremely delicate shift from an inflammatory process to tumorigenesis is a field of major
scientific interest. While the inflammation induced by environmental agents has well known …

Immune system evasion as hallmark of melanoma progression: the role of dendritic cells

M Tucci, A Passarelli, F Mannavola, C Felici… - Frontiers in …, 2019 - frontiersin.org
Melanoma is an immunogenic tumor whose relationship with immune cells resident in the
microenvironment significantly influences cancer cell proliferation, progression, and …

The role of the immune system in cutaneous squamous cell carcinoma

MJ Bottomley, J Thomson, C Harwood… - International journal of …, 2019 - mdpi.com
Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer. In
immunosuppressed populations it is a source of considerable morbidity and mortality due to …

Tissue-infiltrating immune cells as prognostic markers in oral squamous cell carcinoma: a systematic review and meta-analysis

E Hadler-Olsen, AM Wirsing - British journal of cancer, 2019 - nature.com
Background Various immune cells have been suggested as prognostic markers for cancer
patients. In this article, we present a systematic review and meta-analysis of studies …

Langerhans cell origin and regulation

M Collin, P Milne - Current opinion in hematology, 2016 - journals.lww.com
Langerhans cell origin and regulation : Current Opinion in Hematology Langerhans cell origin
and regulation : Current Opinion in Hematology Log in or Register Subscribe to journalSubscribe …