Thyroid hormone transporters at the plasma membrane govern intracellular bioavailability of
thyroid hormone. Monocarboxylate transporter (MCT) 8 and MCT10, organic anion …

The cellular influx and efflux of thyroid hormones are facilitated by transmembrane protein
transporters. Of these transporters, monocarboxylate transporter 8 (MCT8) is the only one …

Lysosomes are membrane-bound endocytic organelles that play a major role in degrading
cell macromolecules and recycling their building blocks. A comprehensive knowledge of the …

The monocarboxylate transporter Mct10 (Slc16a10; T-type amino acid transporter) facilitates
the cellular transport of thyroid hormone (TH) and shows an overlapping expression with the …

Congenital hypothyroidism (CH) is the most common congenital endocrine disorder. The
early treatment of CH patients has successfully improved the prognosis and management of …

Context: The clinical effectiveness of ablative radioiodine treatment of thyroid tumors is
limited by the availability of the sodium iodide symporter (NIS) at the plasma membrane …

Although thyroid‐stimulating hormone (TSH) is known to be a major regulator of thyroid
hormone biosynthesis and thyroid growth, insulin‐like growth factor 1 (IGF‐1) is required for …

The PTTG1-binding factor (PBF/PTTG1IP) has an emerging repertoire of roles, especially in
thyroid biology, and functions as a protooncogene. High PBF expression is independently …

The PTTG1‐binding factor (PBF) is a transforming gene capable of eliciting tumor formation
in xenograft models. However, the precise role of PBF in tumorigenesis and its prognostic …

Abstract Monocarboxylate transporter 8 (MCT8) is a thyroid hormone (TH)-specific
transporter. Mutations in the MCT8 gene are associated with Allan-Herndon-Dudley …