Plasmodium sporozoite transmission is a critical population bottleneck in parasite life-cycle
progression and, hence, a target for prophylactic drugs and vaccines. The recent progress of …

Sporozoites are the infective stage of the malaria parasite. They are deposited in the skin by
infected Anopheles mosquitoes and must penetrate cell barriers in the skin and liver …

For those stricken with malaria, the classic clinical symptoms are caused by the parasite's
cyclic infection of red blood cells. However, this erythrocytic phase of the parasite's life cycle …

Parasites of the genus Plasmodium, the etiological agent of malaria, are transmitted through
the bite of anopheline mosquitoes, which deposit sporozoites into the host skin. Sporozoites …

Background Up to 40% of the world's population is at risk for Plasmodium vivax malaria, a
disease that imposes a major public health and economic burden on endemic countries …

The Plasmodium parasite, the causative agent of malaria, is an excellent model for
immunomic-based approaches to vaccine development. The Plasmodium parasite has a …

Pathogenic microbes rely on environmental cues to initiate key events during infection such
as differentiation, motility, egress and invasion of cells or tissues. Earlier investigations …

A series of 36 new phenylsulfanylmethyl [1, 4] naphthoquinones (7–42) were synthesized by
a three-component reaction that involves lawsone, the appropriate aldehyde and thiols with …

The phylum Apicomplexa comprises a group of obligate intracellular parasites that alternate
between intracellular replicating stages and actively motile extracellular forms that move …

A hallmark of Plasmodium development inside its mammalian victim is the remarkable
restriction to the host species. Adaptation to an intracellular life style in specific target cells is …