Infection of cervical epithelium with high-risk human papilloma virus (hrHPV) might result in
productive or transforming cervical intraepithelial neoplasia (CIN) lesions, the morphology of …

Cervical cancer screening will rely, increasingly, on HPV testing as a primary screen. The
requirement for triage tests which can delineate clinically significant infection is thus …

This review elaborates on the accuracy and feasibility of human papillomavirus (HPV) self‐
sampling, ie, offering self‐sampling of (cervico‐) vaginal cell material by women themselves …

Background Cytology is a widely used method of triaging women who test positive for
human papillomavirus (HPV). However, self-sampled specimens, which can substantially …

The clearly higher sensitivity and reproducibility of human papillomavirus (HPV) DNA testing
for high-grade cervical intraepithelial neoplasia (CIN) has led to widespread calls to …

A biomarker is a molecular target analyzed in a qualitative or quantitative manner to detect
and diagnose the presence of a disease, to predict the outcome and the response to a …

Cervical cancer is the most prevalent gynecologic malignancy, especially in women of low-
and middle-income countries (LMICs). With a better understanding of the etiology and …

Primary testing for human papillomavirus (HPV) in cervical screening requires triage to
differentiate women with transient infection from those with persistent infection who require …

Objectives DNA methylation analysis of cancer-related genes is a promising tool for HPV-
positive women to identify those with cervical (pre) cancer (CIN3+) in need of treatment …

Cervical neoplasia‐specific biomarkers, eg DNA methylation markers, with high sensitivity
and specificity are urgently needed to improve current population‐based screening on (pre) …