Stromal cells in the tumor microenvironment: accomplices of tumor progression?

Y Zhao, M Shen, L Wu, H Yang, Y Yao, Q Yang… - Cell Death & …, 2023 - nature.com
The tumor microenvironment (TME) is made up of cells and extracellular matrix (non-cellular
component), and cellular components include cancer cells and non-malignant cells such as …

Mesenchymal stem cells—potential applications in kidney diseases

B Bochon, M Kozubska, G Surygała… - International journal of …, 2019 - mdpi.com
Mesenchymal stem cells constitute a pool of cells present throughout the lifetime in
numerous niches, characteristic of unlimited replication potential and the ability to …

[HTML][HTML] Roles of mesenchymal stromal cells in the head and neck cancer microenvironment

MC de Miranda, MIA de Melo, P da Silva Cunha… - Biomedicine & …, 2021 - Elsevier
Head and neck cancer (HNC), a common malignancy worldwide, is associated with high
morbidity and mortality rates. Squamous cell carcinoma is the most common HNC type …

Opposing MMP-9 Expression in Mesenchymal Stromal Cells and Head and Neck Tumor Cells after Direct 2D and 3D Co-Culture

A Waltera, D Schulz, N Schaefer, S Stoeckl… - International Journal of …, 2023 - mdpi.com
Bone marrow-derived mesenchymal stromal cells (BMSCs) respond to a variety of tumor cell-
derived signals, such as inflammatory cytokines and growth factors. As a result, the …

Synergistic effects of mesenchymal stem cell transplantation and repetitive transcranial magnetic stimulation on promoting autophagy and synaptic plasticity in …

F Wang, C Zhang, S Hou, X Geng - The Journals of Gerontology …, 2019 - academic.oup.com
Repetitive transcranial magnetic stimulation (rTMS) and mesenchymal stem cells (MSCs)
transplantation both showed therapeutic effects on cognition impairment in vascular …

SPINK7 expression changes accompanied by HER2, P53 and RB1 can be relevant in predicting oral squamous cell carcinoma at a molecular level

G Pennacchiotti, F Valdés-Gutiérrez… - Scientific Reports, 2021 - nature.com
The oral squamous cell carcinoma (OSCC), which has a high morbidity rate, affects patients
worldwide. Changes in SPINK7 in precancerous lesions could promote oncogenesis. Our …

Pro-tumorigenic macrophage infiltration in oral squamous cell carcinoma and possible macrophage-aimed therapeutic interventions

F Bruna, P Scodeller - Frontiers in oncology, 2021 - frontiersin.org
In Oral Squamous Cell Carcinomas (OSCC), as in other solid tumors, stromal cells strongly
support the spread and growth of the tumor. Macrophages in tumors (tumor-associated …

The effects of mesenchymal stem cells on oral cancer and possible therapy regime

T Yang, S Tang, S Peng, G Ding - Frontiers in genetics, 2022 - frontiersin.org
Mesenchymal stem cells (MSCs) are characterized by self-renewal, rapid proliferation,
multipotent differentiation, and low immunogenicity. In addition, the tropism of MSCs towards …

The potential of mesenchymal stromal cells in neuroblastoma therapy for delivery of anti-cancer agents and hematopoietic recovery

C Hochheuser, NY Kunze, GAM Tytgat… - Journal of personalized …, 2021 - mdpi.com
Neuroblastoma is one of the most common pediatric cancers and a major cause of cancer-
related death in infancy. Conventional therapies including high-dose chemotherapy, stem …

Allogeneic Mesenchymal Stem Cells After In Vivo Transplantation: A Review

DB Asserson - Cellular Reprogramming, 2023 - liebertpub.com
Autologous mesenchymal stem cells (MSCs) are ideal for tissue regeneration because of
their ability to circumvent host rejection, but their procurement and processing present …