The Golgi apparatus plays a central role in normal cell physiology by promoting cell survival,
facilitating proliferation, and enabling cell-cell communication and migration. These roles …

The Golgi apparatus is a central intracellular membrane-bound organelle with key functions
in trafficking, processing, and sorting of newly synthesized membrane and secretory proteins …

Protein glycosylation is one of the most abundant post‐translational modifications. However,
detailed analysis of O‐linked glycosylation, a major type of protein glycosylation, has been …

Cancers grow within tissues through molecular mechanisms still unclear. Invasiveness
correlates with perturbed O-glycosylation, a covalent modification of cell-surface proteins …

Background While the underlying causes of cancer are genetic modifications, changes in
cellular states mediate cancer development. Tumor cells display markedly changed …

The Golgi apparatus-complex is a highly dynamic organelle which is considered the “heart”
of intracellular transportation. Since its discovery by Camillo Golgi in 1873, who described it …

The glycoproteome, the ensemble of glycans and their carrier proteins, plays major roles in
multicellular life by regulating cell interactions with their environment. How information is …

Accurate cellular replication balances the biogenesis and turnover of complex structures. In
the apicomplexan parasite Toxoplasma gondii, daughter cells form within an intact mother …

In humans, the UDP-N-α-D galactosamine: polypeptide N-acetylgalactosaminyltransferases
family (ppGalNAc-Ts, GalNAc-Ts or GALNTs) comprises 20 isoenzymes. They are …

Cannabidiol (CBD), a nonpsychoactive phytocannabinoid, has recently emerged as a
potential cytotoxic agent in addition to its ameliorative activity in chemotherapy-associated …