Flavonoids: an overview

AN Panche, AD Diwan, SR Chandra - Journal of nutritional science, 2016 - cambridge.org
Flavonoids, a group of natural substances with variable phenolic structures, are found in
fruits, vegetables, grains, bark, roots, stems, flowers, tea and wine. These natural products …

Plant polyphenols as antioxidant and antibacterial agents for shelf‐life extension of meat and meat products: Classification, structures, sources, and action …

C Papuc, GV Goran, CN Predescu… - … Reviews in Food …, 2017 - Wiley Online Library
Oxidative processes and meat spoilage bacteria are major contributors to decreasing the
shelf‐life of meat and meat products. Oxidative processes occur during processing, storage …

Chemistry and biochemistry of dietary polyphenols

R Tsao - Nutrients, 2010 - mdpi.com
Polyphenols are the biggest group of phytochemicals, and many of them have been found in
plant-based foods. Polyphenol-rich diets have been linked to many health benefits. This …

Synthesis and biological evaluation of 4-(1, 2, 3-triazol-1-yl) coumarin derivatives as potential antitumor agents

W Zhang, Z Li, M Zhou, F Wu, X Hou, H Luo… - Bioorganic & medicinal …, 2014 - Elsevier
In this research, a series of 4-(1, 2, 3-triazol-1-yl) coumarin conjugates were synthesized and
their anticancer activities were evaluated in vitro against three human cancer cell lines …

Metabolic engineering of microbial cell factories for biosynthesis of flavonoids: A review

H Lou, L Hu, H Lu, T Wei, Q Chen - Molecules, 2021 - mdpi.com
Flavonoids belong to a class of plant secondary metabolites that have a polyphenol
structure. Flavonoids show extensive biological activity, such as antioxidative, anti …

Effect of natural polyphenols on CYP metabolism: implications for diseases

EA Korobkova - Chemical research in toxicology, 2015 - ACS Publications
Cytochromes P450 (CYPs) are a large group of hemeproteins located on mitochondrial
membranes or the endoplasmic reticulum. They play a crucial role in the metabolism of …

Simple coumarins: privileged scaffolds in medicinal chemistry

MFM Borges, FMF Roleira… - … Chemistry: Volume 4, 2009 - benthamdirect.com
Coumarins, also known as benzopyrones, are present in remarkable amounts in plants,
although their presence has also been detected in microorganisms and animal sources. The …

Palladium-catalyzed oxidative Heck coupling reaction for direct synthesis of 4-arylcoumarins using coumarins and arylboronic acids

Y Li, Z Qi, H Wang, X Fu, C Duan - The Journal of Organic …, 2012 - ACS Publications
An efficient protocol for the direct synthesis of 4-arylcoumarins via palladium-catalyzed
oxidative Heck coupling reaction of coumarins and arylboronic acids was developed. 4 …

The structure characteristics, biosynthesis and health benefits of naturally occurring rare flavonoids

S Bo, SK Chang, Y Chen, Z Sheng… - Critical Reviews in …, 2024 - Taylor & Francis
Rare flavonoids, a special subclass of naturally occurring flavonoids with diverse structures
including pterocarpans, aurones, neoflavonoids, homoisoflavones, diphenylpropanes …

In vitro and in silico biological studies of 4-phenyl-2-quinolone (4-PQ) derivatives as anticancer agents

YF Chen, B Lawal, LJ Huang, SC Kuo, MR Sumitra… - Molecules, 2023 - mdpi.com
Our previous study found that 2-phenyl-4-quinolone (2-PQ) derivatives are antimitotic
agents, and we adopted the drug design concept of scaffold hopping to replace the 2 …