A new era of macrophage-based cell therapy

YR Na, SW Kim, SH Seok - Experimental & Molecular Medicine, 2023 - nature.com
Macrophages are essential innate immune cells found throughout the body that have
protective and pathogenic functions in many diseases. When activated, macrophages can …

Recent Advances of Platinum‐Based Anticancer Complexes in Combinational Multimodal Therapy

T Zhong, J Yu, Y Pan, N Zhang, Y Qi… - Advanced Healthcare …, 2023 - Wiley Online Library
Platinum drugs with manifest therapeutic effects are widely used, but their systemic toxicity
and the drug resistance acquired by cancer cells limit their clinical applications. Thus, the …

Photocatalytic Pt (IV)‐Coordinated Carbon Dots for Precision Tumor Therapy

D Guo, JH Lei, D Rong, T Zhang, B Zhang… - Advanced …, 2022 - Wiley Online Library
Rapid, efficient, and precise cancer therapy is highly desired. Here, this work reports
solvothermally synthesized photoactivatable Pt (IV)‐coordinated carbon dots (Pt‐CDs) and …

Breakthroughs in cancer immunotherapy: an overview of T cell, NK cell, Mφ, and DC-based treatments

S Lee, TD Kim - International Journal of Molecular Sciences, 2023 - mdpi.com
Efforts to treat cancer using chimeric antigen receptor (CAR)-T therapy have made
astonishing progress and clinical trials against hematopoietic malignancies have …

Biohybrid magnetic microrobots: An intriguing and promising platform in biomedicine

S Zhu, Y Cheng, J Wang, G Liu, T Luo, X Li, S Yang… - Acta Biomaterialia, 2023 - Elsevier
Biohybrid magnetic microrobots (BMMs) have emerged as an exciting class of microrobots
and have been considered as a promising platform in biomedicine. Many microorganisms …

Imaging Identifies Superior Inflammation Targeting of M1 Macrophages for Cryo‐Shocked Cell Pulmonary Drug Delivery to Treat Acute Lung Injury

X Wang, Y Liu, Y Fan, J Yan, G Yan… - Advanced …, 2024 - Wiley Online Library
In the realm of combating acute lung injury (ALI) induced by a myriad of triggers including
sepsis, pneumonia, aspiration, trauma, and pancreatitis, macrophages emerge as crucial …

Metal–Drug Coordination Nanoparticles and Hydrogels for Enhanced Delivery

KY Wong, Z Nie, MS Wong, Y Wang… - Advanced Materials, 2024 - Wiley Online Library
Drug delivery is a key component of nanomedicine, and conventional delivery relies on the
adsorption or encapsulation of drug molecules to a nanomaterial. Many delivery vehicles …

Recent advances in nanocarriers for clinical platinum (II) anticancer drugs

JJ Zhang, QJ Xu, Y Zhang, Q Zhou, R Lv, Z Chen… - Coordination Chemistry …, 2024 - Elsevier
Platinum (II) drugs have been one of the most commonly used anticancer drugs in clinic.
However, drug resistance and severe toxic effects limit their clinical applications. Developing …

Macrophage-based microrobots for anticancer therapy: recent progress and future perspectives

VD Nguyen, JO Park, E Choi - Biomimetics, 2023 - mdpi.com
Macrophages, which are part of the mononuclear phagocytic system, possess sensory
receptors that enable them to target cancer cells. In addition, they are able to engulf large …

Self-assembled methodologies for the construction of DNA nanostructures and biological applications

R Ye, Y Wang, Y Liu, P Cai, J Song - Biomaterials Science, 2024 - pubs.rsc.org
Over the past decades, deoxyribonucleic acid (DNA), as a versatile building block, has been
widely employed to construct functionalized nanostructures. Among the diverse types of …