Silibinin, a natural flavanone, derived from the milk thistle plant (Silybum marianum), was
illustrated for several medicinal uses such as liver-protective, anti-oxidant, anti-cancer, anti …

Nitric oxide, carbon monoxide and hydrogen sulfide are three endogenous gasotransmitters
that serve a role in regulating normal and pathological cellular activities. They can stimulate …

Diagnosis of breast cancer (BC) by using sensitive and specific biomarkers is necessary.
Cell-free DNA is a candidate biomarker in various cancers. Contrasting, shorted uniformed …

Silybin-phosphatidylcholine is an orally bioavailable complex of silybin, a polyphenolic
flavonolignan derived from milk thistle, endowed with potential anticancer activity in …

Emerging data suggest that impaired nitric oxide (NO) homeostasis has a key role in
development of cardiometabolic disorders. The association between circulating levels of NO …

Objectives The basic fibroblast growth factor (bFGF)/fibroblast growth factor receptor (FGFR)
signal transductional pathway plays an important role not only in tumour, but also in tumour …

Serum sFas and p53 protein have been observed in breast cancer patients, but their clinical
usefulness for diagnosis and therapy monitoring has not been clarified. The aim of this study …

Human tumors are usually not spontaneously eliminated by the immune system and
therapeutic vaccination of cancer patients with defined antigens is followed by tumor …

Results Reference values of serum concentrations of NO metabolites (nitrate+ nitrite or NOx)
were 11.5-76.4, 10.1-65.6, and 10.3-66.8 μmol/L in men, women, and the total population …

Introduction We examined the interactive effects of copper (Cu) and overweight (overweight)
and obesity on outcomes of burn patients. We posited that higher baseline Cu among burn …