Application of molecular dynamics simulation in the field of food enzymes: Improving the thermal-stability and catalytic ability

Z Huang, D Ni, Z Chen, Y Zhu, W Zhang… - Critical Reviews in Food …, 2024 - Taylor & Francis
Enzymes can produce high-quality food with low pollution, high function, high acceptability,
and medical aid. However, most enzymes, in their native form, do not meet the industrial …

Recent advances in β-glucosidase sequence and structure engineering: a brief review

B Ouyang, G Wang, N Zhang, J Zuo, Y Huang, X Zhao - Molecules, 2023 - mdpi.com
β-glucosidases (BGLs) play a crucial role in the degradation of lignocellulosic biomass as
well as in industrial applications such as pharmaceuticals, foods, and flavors. However, the …

Computer-aided tunnel engineering: a promising strategy for improving lipase applications in esterification reactions

W Chong, Y Qi, L Ji, Z Zhang, Z Lu, B Nian, Y Hu - ACS Catalysis, 2023 - ACS Publications
Esterification is one of the most important reactions in organic synthesis and industrial
applications. The applications of lipases in esterification are increasingly widespread and …

The mining of thermostable β-glucosidase for tea aroma enhancement under brewing conditions

Q Lin, C Peng, K Yu, Y Lin, Y Xu, L Li, H Ni, F Chen - Food Chemistry, 2024 - Elsevier
The β-glucosidases known to improve tea aroma are all mesothermal enzymes, limiting their
use under brewing conditions. Based on the properties analysis and molecular docking, the …

Enzymatic glycosylation strategies in the production of bioactive compounds

A Andreu, M Ćorović, C Garcia-Sanz, AS Santos… - Catalysts, 2023 - mdpi.com
Enzymatic glycosylation is a versatile and sustainable biotechnological approach that plays
a pivotal role in the production of bioactive compounds. This process involves the enzymatic …

Engineering polysaccharide hydrolases in the product-releasing cleft to alter their product profiles

M Wang, Y Xian, Z Lu, P Wu, G Zhang - International Journal of Biological …, 2024 - Elsevier
Polysaccharide hydrolases are enzymes capable of hydrolyzing polysaccharides to
generate oligosaccharides that have diverse applications in the food, feed and …

Enzymatic biosynthesis of D-galactose derivatives: Advances and perspectives

J Liu, X Feng, L Liang, L Sun, D Meng - International Journal of Biological …, 2024 - Elsevier
D-Galactose derivatives, including galactosyl-conjugates and galactose-upgrading
compounds, provide various physiological benefits and find applications in industries such …

Effects of synonymous mutations on kinetic properties and structure of firefly luciferase: Molecular dynamics simulation, molecular docking, RNA folding, and …

M Mortazavi, M Torkzadeh-Mahani, M Rahimi… - International Journal of …, 2023 - Elsevier
Although synonymous mutations have long been thought to lack striking results, a growing
body of research shows these mutations have highly variable effects. In this study, the …

[HTML][HTML] Engineering of Substrate-Binding Domain to Improve Catalytic Activity of Chondroitin B Lyase with Semi-Rational Design

M Tian, YY Xu, YN Li, S Yu, YL Wang, XL Ma… - Current Issues in …, 2024 - mdpi.com
Dermatan sulfate and chondroitin sulfate are dietary supplements that can be utilized as
prophylactics against thrombus formation. Low-molecular-weight dermatan sulfate (LMWDS) …

Cloning, expression and mutation of a novel thermophilic GH1 β-galactosidase from Vulcanisaeta thermophila with transglycosylation activity for tyrosol galactoside …

Q Xing, X Wang, Q Li, C Lu, Y Wu, J Pei, L Zhao - Molecular Catalysis, 2024 - Elsevier
Abstract β-Galactosidase is a crucial class of biocatalysts, renowned for its ability to catalyze
the hydrolysis of non-reducing terminal β-d-galactoside bonds, while also demonstrating …