Inflammatory mediators in the pathogenesis of periodontitis
T Yucel-Lindberg, T Båge - Expert reviews in molecular medicine, 2013 - cambridge.org
Periodontitis is a chronic inflammatory condition of the periodontium involving interactions
between bacterial products, numerous cell populations and inflammatory mediators. It is …
between bacterial products, numerous cell populations and inflammatory mediators. It is …
Prostaglandin E2 and pain—an update
A Kawabata - Biological and Pharmaceutical Bulletin, 2011 - jstage.jst.go.jp
Prostaglandin E2 (PGE2), a cyclooxygenase (COX) product, is the best known lipid mediator
that contributes to inflammatory pain. Nonsteroidal anti-inflammatory drugs (NSAIDs) …
that contributes to inflammatory pain. Nonsteroidal anti-inflammatory drugs (NSAIDs) …
A review on mPGES-1 inhibitors: From preclinical studies to clinical applications
F Bergqvist, R Morgenstern, PJ Jakobsson - Prostaglandins & other lipid …, 2020 - Elsevier
Abstract Prostaglandin E 2 (PGE 2) is a lipid mediator of inflammation and cancer
progression. It is mainly formed via metabolism of arachidonic acid by cyclooxygenases …
progression. It is mainly formed via metabolism of arachidonic acid by cyclooxygenases …
Nonsteroidal anti‐inflammatory therapy: a journey toward safety
C Pereira‐Leite, C Nunes, SK Jamal… - Medicinal research …, 2017 - Wiley Online Library
The efficacy of nonsteroidal anti‐inflammatory drugs (NSAIDs) against inflammation, pain,
and fever has been supporting their worldwide use in the treatment of painful conditions and …
and fever has been supporting their worldwide use in the treatment of painful conditions and …
Carbazole scaffold in medicinal chemistry and natural products: A review from 2010-2015
L S. Tsutsumi, D Gündisch, D Sun - Current Topics in Medicinal …, 2016 - benthamdirect.com
9H-carbazole is an aromatic molecule that is tricyclic in nature, with two benzene rings fused
onto a 5-membered pyrrole ring. Obtained from natural sources or by synthetic routes, this …
onto a 5-membered pyrrole ring. Obtained from natural sources or by synthetic routes, this …
Room-temperature chemoselective reduction of nitro groups using non-noble metal nanocatalysts in water
Purely aqueous-phase chemoselective reduction of a wide range of aromatic and aliphatic
nitro substrates has been performed in the presence of inexpensive Ni-and Co-based …
nitro substrates has been performed in the presence of inexpensive Ni-and Co-based …
Mechanistic aspects of COX-2 expression in colorectal neoplasia
Abstract The cyclooxygenase-2 (COX-2) enzyme catalyzes the rate-limiting step of
prostaglandin formation in pathogenic states and a large amount of evidence has …
prostaglandin formation in pathogenic states and a large amount of evidence has …
Highly efficient and selective photocatalytic reduction of nitroarenes using the Ni 2 P/CdS catalyst under visible-light irradiation
WZ Gao, Y Xu, Y Chen, WF Fu - Chemical Communications, 2015 - pubs.rsc.org
A highly efficient and selective heterogeneous photocatalytic system for nitro reduction to
amino organics was established using CdS, Ni2P and Na2S/Na2SO3 as a photosensitizer …
amino organics was established using CdS, Ni2P and Na2S/Na2SO3 as a photosensitizer …
Microsomal prostaglandin E2 synthase-1 and its inhibitors: Molecular mechanisms and therapeutic significance
YY Zhang, YD Yao, JF Luo, ZQ Liu, YM Huang… - Pharmacological …, 2022 - Elsevier
Inflammation is closely linked to the abnormal phospholipid metabolism chain of
cyclooxygenase-2/microsomal prostaglandin E 2 synthase-1/prostaglandin E 2 (COX …
cyclooxygenase-2/microsomal prostaglandin E 2 synthase-1/prostaglandin E 2 (COX …
Identification and development of mPGES-1 inhibitors: where we are at?
HH Chang, EJ Meuillet - Future medicinal chemistry, 2011 - Taylor & Francis
Microsomal prostaglandin E synthase-1 (mPGES-1) is the terminal synthase responsible for
the synthesis of the pro-tumorigenic prostaglandin E2 (PGE2). mPGES-1 is overexpressed …
the synthesis of the pro-tumorigenic prostaglandin E2 (PGE2). mPGES-1 is overexpressed …