Hypervalent‐Iodine (III)‐Mediated Oxidative Methodology for the Synthesis of Fused Triazoles

R Kamal, V Kumar, R Kumar - Chemistry–An Asian Journal, 2016 - Wiley Online Library
The organic chemistry of hypervalent organoiodine compounds has been an area of
unprecedented development. This surge in interest in the use of hypervalent iodine …

Eucalyptol: a new solvent for the synthesis of heterocycles containing oxygen, sulfur and nitrogen

JF Campos, MC Scherrmann, S Berteina-Raboin - Green chemistry, 2019 - pubs.rsc.org
We report here the first investigation of the use of eucalyptol as a new solvent for organic
transformations. Heterocycles containing oxygen, sulfur and nitrogen were chosen as …

A Predictive Model Towards Site‐Selective Metalations of Functionalized Heterocycles, Arenes, Olefins, and Alkanes using TMPZnCl⋅ LiCl

M Balkenhohl, H Jangra, IS Makarov… - Angewandte Chemie …, 2020 - Wiley Online Library
The development of a predictive model towards site‐selective deprotometalation reactions
using TMPZnCl⋅ LiCl is reported (TMP= 2, 2, 6, 6‐tetramethylpiperidinyl). The pKa values of …

A Focused Review on Oxidation of Hydrazones Using Hypervalent Iodine Reagents

M Sihag, M Kinger, DK Aneja - ChemistrySelect, 2025 - Wiley Online Library
Hydrazones are described as synthetic equivalents to the carbonyl group and possess high
synthon value. Herein, we compile the oxidative transformation of hydrazones using …

An update on direct C–H bond functionalization of nitrogen-containing fused heterocycles

J Aziz, S Piguel - Synthesis, 2017 - thieme-connect.com
This report highlights the recent advances in direct C–H bond functionalization of 5, 5-and 6,
5-fused heterocycles containing at least two nitrogen atoms. Besides C–C bond formation, C …

Synthesis and in vitro evaluation of diverse heterocyclic diphenolic compounds as inhibitors of DYRK1A

Q Zhou, TA Reekie, RH Abbassi, DI Venkata… - Bioorganic & medicinal …, 2018 - Elsevier
Dual-specificity tyrosine phosphorylation-related kinase 1A (DYRK1A) is a dual-specificity
protein kinase that catalyses phosphorylation and autophosphorylation. Higher DYRK1A …

tele-Substitution Reactions in the Synthesis of a Promising Class of 1,2,4-Triazolo[4,3-a]pyrazine-Based Antimalarials

M Korsik, EG Tse, DG Smith, W Lewis… - The Journal of …, 2020 - ACS Publications
We have discovered and studied a tele-substitution reaction in a biologically important
heterocyclic ring system. Conditions that favor the tele-substitution pathway were identified …

A Novel Mild Method for the Synthesis of 3-Amino-4-(5-aryl-1H-1,2,4-Triazol-3-yl)Furazans

SS Semyakin, MI Struchkova… - Chemistry of Heterocyclic …, 2016 - Springer
A Novel Mild Method for the Synthesis of 3-Amino-4-(5-aryl-1H-1,2,4-Triazol-3-yl)Furazans |
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НОВЫЙ МЯГКИЙ МЕТОД СИНТЕЗА 3-АМИНО-4-(5-АРИЛ-1H-1,2,4-ТРИАЗОЛ-3-ИЛ)ФУРАЗАНОВ

СС Семякин, МИ Стручкова… - Chemistry of Heterocyclic …, 2016 - osi131.osi.lv
Попытки получить триазол из N'-[(тиофен-2-ил)-метилиден] амидразона 2g приводят к
сильному осмолению, что, вероятно, обусловлено окислением тиенильного фрагмента …

Design Synthesis and Biological Evaluation of DYRK1A Inhibitors

Q Zhou - 2017 - ses.library.usyd.edu.au
DYRK1A is a dual-specificity protein kinase that catalyses not only autophosphorylation on
its tyrosine residue but the phosphorylation of serine and threonine residues in its …