Open questions about the roles of DnaA, related proteins, and hyperstructure dynamics in the cell cycle
M Kohiyama, J Herrick, V Norris - Life, 2023 - mdpi.com
The DnaA protein has long been considered to play the key role in the initiation of
chromosome replication in modern bacteria. Many questions about this role, however …
chromosome replication in modern bacteria. Many questions about this role, however …
The in vivo measurement of replication fork velocity and pausing by lag-time analysis
An important step towards understanding the mechanistic basis of the central dogma is the
quantitative characterization of the dynamics of nucleic-acid-bound molecular motors in the …
quantitative characterization of the dynamics of nucleic-acid-bound molecular motors in the …
Bacterial replication initiation as precision control by protein counting
Balanced biosynthesis is the hallmark of bacterial cell physiology, where the concentrations
of stable proteins remain steady. However, this poses a conceptual challenge to modeling …
of stable proteins remain steady. However, this poses a conceptual challenge to modeling …
Slowest possible replicative life at frigid temperatures for yeast
Determining whether life can progress arbitrarily slowly may reveal fundamental barriers to
staying out of thermal equilibrium for living systems. By monitoring budding yeast's slowed …
staying out of thermal equilibrium for living systems. By monitoring budding yeast's slowed …
Rationally designed chromosome fusion does not prevent rapid growth of Vibrio natriegens
L Ramming, D Stukenberg, MC Sánchez Olmos… - Communications …, 2024 - nature.com
DNA replication is essential for the proliferation of all cells. Bacterial chromosomes are
replicated bidirectionally from a single origin of replication, with replication proceeding at …
replicated bidirectionally from a single origin of replication, with replication proceeding at …
[HTML][HTML] Efficient CRISPR-Cas12f1-Mediated Multiplex Bacterial Genome Editing via Low-Temperature Recovery
SR Lim, HJ Kim, SJ Lee - Journal of microbiology and …, 2024 - ncbi.nlm.nih.gov
CRISPR-Cas system is being used as a powerful genome editing tool with developments
focused on enhancing its efficiency and accuracy. Recently, the miniature CRISPR-Cas12f1 …
focused on enhancing its efficiency and accuracy. Recently, the miniature CRISPR-Cas12f1 …
Genome replication in asynchronously growing microbial populations
Biological cells replicate their genomes in a well-planned manner. The DNA replication
program of an organism determines the timing at which different genomic regions are …
program of an organism determines the timing at which different genomic regions are …
The high-resolution in vivo measurement of replication fork velocity and pausing by lag-time analysis
An important step towards understanding the mechanistic basis of the central dogma is the
quantitative characterization of the dynamics of nucleic-acid-bound molecular motors in the …
quantitative characterization of the dynamics of nucleic-acid-bound molecular motors in the …
Stochasticity, conflicts, and instability: Biological strategies for optimal growth in a complex environment
D Huang - 2024 - search.proquest.com
Life is complicated. Even in the bacterium Escherichia coli, cell proliferation is dependent on
the maintenance of over 2000 small-molecule metabolites, as well as the synthesis of more …
the maintenance of over 2000 small-molecule metabolites, as well as the synthesis of more …
Open Questions about the Roles of DnaA, Related Proteins and Hyperstructure Dynamics in the Cell Cycle: a Cobblestone in the Pond?
M Kohiyama, J Herrick, V Norris - 2023 - preprints.org
The DnaA protein has long been considered to play the key role in the initiation of
chromosome replication in modern bacteria. Many questions about this role, however …
chromosome replication in modern bacteria. Many questions about this role, however …