Bioactive components and molecular mechanisms of Salvia miltiorrhiza Bunge in promoting blood circulation to remove blood stasis

B Wei, C Sun, H Wan, Q Shou, B Han, M Sheng… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Salvia miltiorrhiza Bunge (SM) is an outstanding
herbal medicine with various traditional effects, especially promoting blood circulation to …

Advances on natural abietane, labdane and clerodane diterpenes as anti-cancer agents: Sources and mechanisms of action

R Acquaviva, GA Malfa, MR Loizzo, J Xiao, S Bianchi… - Molecules, 2022 - mdpi.com
Extensive research over the past decades has identified numerous phytochemicals that
could represent an important source of anti-cancer compounds. There is an immediate need …

ABA-responsive transcription factor bZIP1 is involved in modulating biosynthesis of phenolic acids and tanshinones in Salvia miltiorrhiza

C Deng, M Shi, R Fu, Y Zhang, Q Wang… - Journal of …, 2020 - academic.oup.com
Phenolic acids and tanshinones are major bioactive ingredients in Salvia miltiorrhiza, which
possess pharmacological activities with great market demand. However, transcriptional …

SmMYB2 promotes salvianolic acid biosynthesis in the medicinal herb Salvia miltiorrhiza

C Deng, Y Wang, F Huang, S Lu… - Journal of integrative …, 2020 - Wiley Online Library
MYB transcription factors play vital roles in plant growth and metabolism. The phytohormone
methyl jasmonate (MeJA) promotes phenolic acid accumulation in the medicinal herb Salvia …

Endophytic fungus Cladosporium tenuissimum DF11, an efficient inducer of tanshinone biosynthesis in Salvia miltiorrhiza roots

H Chen, J Chen, Y Qi, S Chu, Y Ma, L Xu, S Lv… - Phytochemistry, 2022 - Elsevier
Salvia miltiorrhiza is a traditional medicinal plant mainly used for cardiovascular and
cerebrovascular disease treatment. Tanshinones are the main bioactive constituents of S …

A review of auraptene as an anticancer agent

Z Tayarani-Najaran, N Tayarani-Najaran… - Frontiers in …, 2021 - frontiersin.org
Auraptene is a bioactive monoterpene coumarin isolated from Citrus aurantium and Aegle
marmelos that belong to the Rutaceae family. Auraptene can modulate intracellular …

Advanced application of nanotechnology in active constituents of Traditional Chinese Medicines

C Qiu, JZ Zhang, B Wu, CC Xu, HH Pang… - Journal of …, 2023 - Springer
Abstract Traditional Chinese Medicines (TCMs) have been used for centuries for the
treatment and management of various diseases. However, their effective delivery to targeted …

Improved phenolic acid content and bioactivities of Salvia miltiorrhiza hairy roots by genetic manipulation of RAS and CYP98A14

R Fu, M Shi, C Deng, Y Zhang, X Zhang, Y Wang, G Kai - Food chemistry, 2020 - Elsevier
Phenolic acids from Salvia miltiorrhiza have been widely used in nutritious, health-
promoting products with an increasing demand. In the current study, two biosynthetic genes …

Tanshinone IIA targeting cell signaling pathways: A plausible paradigm for cancer therapy

SSM Alam, A Samanta, F Uddin, S Ali… - Pharmacological Reports, 2023 - Springer
Natural compounds originating from plants offer a wide range of pharmacological potential
and have traditionally been used to treat a wide range of diseases including cancer …

[HTML][HTML] Potential of natural products in osteosarcoma treatment: Focus on molecular mechanisms

M Tobeiha, A Rajabi, A Raisi, M Mohajeri… - Biomedicine & …, 2021 - Elsevier
Osteosarcoma is the most frequent type of bone cancer found in children and adolescents,
and commonly arises in the metaphyseal region of tubular long bones. Standard therapeutic …