Abstract The Ca2+-sensing receptor (CaSR) is a dimeric family CG protein-coupled receptor
that is expressed in calcitropic tissues such as the parathyroid glands and the kidneys and …

The calcium-sensing receptor (CaSR) is a class CG protein–coupled receptor that responds
to multiple endogenous agonists and allosteric modulators, including divalent and trivalent …

Compelling evidence of a cell surface receptor sensitive to extracellular calcium was
observed as early as the 1980s and was finally realized in 1993 when the calcium-sensing …

Pediatric refractory epilepsy is a broad phenotypic spectrum with great genetic
heterogeneity. Next-generation sequencing (NGS) combined with Sanger sequencing could …

The extracellular calcium-sensing receptor (CaSR) is a family C G-protein-coupled receptor
(GPCR) that is expressed at multiple sites, including the parathyroids and kidneys. The …

Extracellular K+, Na+, and Ca 2+ ions all influence the resting membrane potential of the
neuron. However, the mechanisms by which extracellular Na+ and Ca 2+ regulate basal …

The association between primary hyperparathyroidism (PHPT) and acute or chronic
pancreatitis is controversial. For this reason, we conducted a review of the literature over the …

The extracellular calcium-sensing receptor (CaSR) is the first identified G protein–coupled
receptor to be activated by an ion, extracellular calcium (Ca2+). Since the identification of …

RNA–binding proteins have emerged as causal agents of complex neurological diseases.
Mice deficient for neuronal RNA–binding protein CELF4 have a complex neurological …

Following the discovery of the calcium-sensing receptor (CaSR) in 1993, its pivotal role in
disorders of calcium homeostasis such as Familial Hypocalciuric Hypercalcemia (FHH) was …