Bacterial biofilm inhibition: A focused review on recent therapeutic strategies for combating the biofilm mediated infections

R Srinivasan, S Santhakumari, P Poonguzhali… - Frontiers in …, 2021 - frontiersin.org
Biofilm formation is a major concern in various sectors and cause severe problems to public
health, medicine, and industry. Bacterial biofilm formation is a major persistent threat, as it …

Marine bacterial secondary metabolites: A treasure house for structurally unique and effective antimicrobial compounds

R Srinivasan, A Kannappan, C Shi, X Lin - Marine Drugs, 2021 - mdpi.com
The prevalence of antimicrobial resistance reduces the effectiveness of antimicrobial drugs
in preventing and treating infectious diseases caused by pathogenic organisms, such as …

Quinolines-Based SARS-CoV-2 3CLpro and RdRp Inhibitors and Spike-RBD-ACE2 Inhibitor for Drug-Repurposing Against COVID-19: An in silico Analysis

R Alexpandi, JF De Mesquita, SK Pandian… - Frontiers in …, 2020 - frontiersin.org
The novel coronavirus SARS-CoV-2 disease “COVID-19” emerged in China and rapidly
spread to other countries; due to its rapid worldwide spread, the WHO has declared this as a …

Therapeutic importance of Cucurbitaceae: A medicinally important family

PK Mukherjee, S Singha, A Kar, J Chanda… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Medicinal plants of Cucurbitaceae family consist of several
edible fruits and vegetables consumed worldwide since ancient times. The plants of this …

[HTML][HTML] Bacterial biofilm inhibitors: An overview

VC Kalia, SKS Patel, JK Lee - Ecotoxicology and Environmental Safety, 2023 - Elsevier
Bacteria that cause infectious diseases adopt biofilms as one of their most prevalent
lifestyles. Biofilms enable bacteria to tolerate environmental stress and evade antibacterial …

An innovative role for luteolin as a natural quorum sensing inhibitor in Pseudomonas aeruginosa

YF Geng, C Yang, Y Zhang, SN Tao, J Mei, XC Zhang… - Life sciences, 2021 - Elsevier
Aims The emergence of antibiotic tolerance was a tricky problem in the treatment of chronic
Pseudomonas aeruginosa-infected cystic fibrosis and burn victims. The quorum sensing …

Inhibitory Effect of Morin Against Candida albicans Pathogenicity and Virulence Factor Production: An in vitro and in vivo Approaches

G Abirami, R Alexpandi, R Durgadevi… - Frontiers in …, 2020 - frontiersin.org
Candida albicans is considered an exclusive etiologic agent of candidiasis, a very common
fungal infection in human. The expression of virulence factors contributes highly to the …

Tocopherol-assisted magnetic Ag-Fe3O4-TiO2 nanocomposite for photocatalytic bacterial-inactivation with elucidation of mechanism and its hazardous level …

R Alexpandi, G Abirami, B Murugesan… - Journal of Hazardous …, 2023 - Elsevier
In recent years, many endeavours have been prompted with photocatalytic nanomaterials by
the need to eradicate pathogenic microorganisms from water bodies. Herein, a tocopherol …

Caenorhabditis elegans as a powerful tool in natural product bioactivity research

NM Ha, SH Tran, YH Shim, K Kang - Applied Biological Chemistry, 2022 - Springer
In addition to synthetic and semisynthetic compounds, natural products have received much
attention as prolific sources of lead compounds with therapeutic effects on various diseases …

[PDF][PDF] Applications of genetic code expansion technology in eukaryotes

Q Guo, YJ Cao - Protein & Cell, 2024 - academic.oup.com
Unnatural amino acids (UAAs) have gained significant attention in protein engineering and
drug development owing to their ability to introduce new chemical functionalities to proteins …